Gene: IFIT1
Official Full Name: interferon induced protein with tetratricopeptide repeats 1provided by HGNC
Gene Summary: This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00121 | IFIT1 Knockout cell line (HCT 116) | Human | IFIT1 | 1:2~1:4 | Negative | Online Inquiry |
KO37108 | IFIT1 Knockout cell line (HeLa) | Human | IFIT1 | 1:3~1:6 | Negative | Online Inquiry |
KO37109 | IFIT1 Knockout cell line (HEK293) | Human | IFIT1 | 1:3~1:6 | Negative | Online Inquiry |
KO37110 | IFIT1 Knockout cell line (A549) | Human | IFIT1 | 1:3~1:4 | Negative | Online Inquiry |
IFIT1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the Interferon-Inducible Protein 1 (IFIT1) gene, an essential component of the antiviral response and innate immunity. These knockout cell lines serve as a powerful tool for researchers aiming to elucidate the role of the IFIT1 protein in various biological processes, including viral infection responses and immune signaling pathways.
Functionally, these cell lines are designed to facilitate the investigation of IFIT1’s contributions to cellular resistance against viral pathogens. By providing a controlled setting devoid of the IFIT1 gene, researchers can directly assess the impact of IFIT1 on the host’s immune response, including how cells react to viral infections and the subsequent signaling cascades that modulate inflammatory responses. These analyses are critical for understanding pathogenic mechanisms and developing therapeutic strategies.
The scientific significance of IFIT1 Gene Knockout Cell Lines extends beyond basic research; they are invaluable in clinical studies where understanding the variability of immune responses can lead to advancements in tailored medicine. For example, these cell lines can be utilized to screen potential antiviral compounds or to study the effects of therapeutic interventions that modify immune functions, paving the way for enhanced treatment modalities.
When compared to traditional cell lines or models, our IFIT1 Gene Knockout Cell Lines stand out due to their specificity, rigorously validated genetic modification, and comprehensive support documentation provided for experimental design and protocol optimization. These features ensure reliability and reproducibility, which are pivotal in translating research findings into clinical applications.
Researchers, clinicians, and biopharmaceutical companies will find considerable value in the IFIT1 Gene Knockout Cell Lines, as they not only enhance experimental accuracy but also accelerate the discovery of innovative approaches to combat viral diseases. By employing our cell lines, users engage with a product backed by our deep expertise in genetic engineering and commitment to supporting cutting-edge research. We pride ourselves on offering high-quality biological products that empower the scientific community to explore and ultimately unravel the complexities of human health.
Please note that all services are for research use only. Not intended for any clinical use.
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