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ID3 Knockout Cell Lines

Gene: ID3

Official Full Name: inhibitor of DNA binding 3provided by HGNC

Gene Summary: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11539 ID3 Knockout cell line (HeLa) Human ID3 1:3~1:6 Negative Online Inquiry
KO11540 ID3 Knockout cell line (HCT 116) Human ID3 1:2~1:4 Negative Online Inquiry
KO11541 ID3 Knockout cell line (HEK293) Human ID3 1:3~1:6 Negative Online Inquiry
KO11542 ID3 Knockout cell line (A549) Human ID3 1:3~1:4 Negative Online Inquiry

Background

ID3 Gene Knockout Cell Lines are advanced cellular models engineered to provide researchers with invaluable tools for studying the functional roles of the ID3 gene in various biological processes. By employing CRISPR/Cas9 gene-editing technology, these cell lines have been specifically modified to harbor targeted deletions in the ID3 gene, allowing for precise manipulation of cellular pathways and phenotypes. This capability enables scientists to elucidate the gene's involvement in critical processes such as immune response, cell differentiation, and oncogenesis, making it a cornerstone for both basic research and translational studies.

The underlying mechanism of ID3 gene knockout involves the disruption of transcriptional regulation typically influenced by ID3 protein, which plays a pivotal role in modulating T-cell development and function. By studying these knockout models, researchers can gain insights into the pathological consequences of ID3 loss, thereby advancing our understanding of related diseases such as lymphomas and autoimmune disorders. In clinical settings, this can facilitate the identification of novel therapeutic targets and biomarkers.

What sets ID3 Gene Knockout Cell Lines apart from competing models is their high specificity and efficiency, combined with a user-friendly application. Unlike conventional knockout systems that may have off-target effects or limited reproducibility, these cell lines offer consistent performance, allowing for reliable experimentation and conclusions. Additionally, they come with comprehensive cell line characterization data, ensuring that researchers can confidently interpret their findings.

For researchers, clinicians, and pharmaceutical developers, ID3 Gene Knockout Cell Lines present an indispensable resource for advancing knowledge in immunology and cancer biology. The precise capability of these models enhances experimental robustness, ultimately driving innovation across various scientific fields. Our company, recognized for its expertise in cellular biology and genetic engineering, offers a range of high-quality biological products designed to meet the rigorous demands of cutting-edge research. With a commitment to excellence and innovation, we empower our users to achieve their research objectives efficiently and effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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