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HSH2D Knockout Cell Lines

Gene: HSH2D

Official Full Name: hematopoietic SH2 domain containingprovided by HGNC

Gene Summary: T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24420 HSH2D Knockout cell line (HCT 116) Human HSH2D 1:2~1:4 Negative Online Inquiry

Background

HSH2D Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed specifically to facilitate the study of gene function by providing researchers with a system where the HSH2D gene has been effectively disrupted. This is achieved through precision genome editing technologies, such as CRISPR/Cas9, which enables the targeted knockout of the gene, allowing for detailed examination of the resulting phenotypic changes. By eliminating the expression of HSH2D, these cell lines serve as powerful models for investigating the gene's role in various biological processes.

The primary function of HSH2D Gene Knockout Cell Lines is to allow for the exploration of gene interactions and the pathways they influence. Researchers can utilize these cell lines to analyze cellular responses to various stimuli, the impact on metabolic pathways, and the potential involvement of HSH2D in disease mechanisms. This is particularly valuable in the context of understanding complex disorders such as immune-related diseases and cancers where HSH2D may play a pivotal role.

The scientific importance of these cell lines cannot be overstated, as they provide an invaluable resource for both fundamental and applied biomedical research. They facilitate high-throughput screening processes, drug discovery, and the validation of therapeutic targets. Additionally, by using knockout models, scientists can garner insights that would be challenging or impossible to achieve with wild-type cell lines.

What sets HSH2D Gene Knockout Cell Lines apart from alternative offerings is their rigorous validation and standardization, ensuring reproducibility and reliability in experimental results. These cell lines are developed under stringent quality controls, ensuring that researchers have access to a dependable model system that enhances the accuracy of their investigations, thereby saving time and reducing experimental variability.

Researchers and clinicians recognize the exceptional value of utilizing HSH2D Gene Knockout Cell Lines, as these models provide clearer insights into genetic interactions and disease mechanisms. With the increasing demand for precision in genetic studies, these cell lines offer an essential tool to push the boundaries of biomedical research.

At [Your Company Name], we are committed to advancing scientific discovery through our innovative biological products. Our expertise in developing high-quality gene knockout cell lines ensures that researchers and industry professionals have the best resources at their fingertips to drive their groundbreaking work forward.

Please note that all services are for research use only. Not intended for any clinical use.

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