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HS6ST3 Knockout Cell Lines

Gene: HS6ST3

Official Full Name: heparan sulfate 6-O-sulfotransferase 3provided by HGNC

Gene Summary: Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17056 HS6ST3 Knockout cell line (HEK293) Human HS6ST3 1:3~1:6 Negative Online Inquiry

Background

HS6ST3 Gene Knockout Cell Lines are expertly engineered human cell lines designed to elucidate the role of the HS6ST3 gene, which encodes for the heparan sulfate 6-O-sulfotransferase 3 enzyme. This enzyme is crucial for the biosynthesis of heparan sulfate, a glycosaminoglycan involved in various biological processes, including cell signaling, development, and disease pathology. The knockout of HS6ST3 allows researchers to investigate the downstream effects of altered heparan sulfate modifications on cellular behavior, including proliferation, migration, and differentiation.

The mechanisms underlying the function of HS6ST3 involve the modification of heparan sulfate chains, influencing numerous cellular interactions and pathways. By utilizing our knockout cell lines, researchers can directly observe the impact of HS6ST3 in conditions such as tumor progression or viral infections, where altered heparan sulfate structures may facilitate or hinder disease states. This model thus serves as a vital tool for exploring therapeutic strategies targeted at modulating heparan sulfate interactions.

From a scientific perspective, HS6ST3 Gene Knockout Cell Lines are invaluable for preclinical research, drug discovery, and the study of genetic pathways associated with various diseases. The availability of these specific cell lines enables a level of precision and insight that is often lacking in traditional models, allowing for an in-depth exploration of gene function and its implications in human health.

One of the primary advantages of our HS6ST3 knockout lines is their high specificity and reliability when compared to alternative methods, such as transient transfection or chemical inhibition. These engineered cell lines provide a stable platform for long-term studies, ensuring reproducibility and consistent results over time. Furthermore, they are readily adaptable for high-throughput screening applications, which is essential for modern research environments.

As a leading provider of biological products, our commitment to quality and innovation ensures that our HS6ST3 Gene Knockout Cell Lines are produced under stringent laboratory standards, utilizing cutting-edge molecular biology techniques. This expertise translates into products that not only meet but exceed the expectations of researchers and clinicians aiming to unlock new discoveries and advance the field of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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