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HOOK2 Knockout Cell Lines

Gene: HOOK2

Official Full Name: hook microtubule tethering protein 2provided by HGNC

Gene Summary: Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26960 HOOK2 Knockout cell line (HeLa) Human HOOK2 1:3~1:6 Negative Online Inquiry
KO26961 HOOK2 Knockout cell line (HCT 116) Human HOOK2 1:2~1:4 Negative Online Inquiry
KO26962 HOOK2 Knockout cell line (HEK293) Human HOOK2 1:3~1:6 Negative Online Inquiry
KO26963 HOOK2 Knockout cell line (A549) Human HOOK2 1:3~1:4 Negative Online Inquiry

Background

HOOK2 Gene Knockout Cell Lines are genetically engineered cellular models that facilitate the study of the HOOK2 gene's role in cellular processes. These cell lines feature a complete knockout of the HOOK2 gene, achieved through state-of-the-art CRISPR/Cas9 technology, which enables precise edits to the genome. The absence of HOOK2 allows researchers to observe the resultant phenotypic and physiological changes, shedding light on the gene's specific contributions to various biological pathways.

The primary function of HOOK2 appears to be related to cellular trafficking and cytoskeletal dynamics, which are critical for maintaining cellular architecture and function. By studying these knockout cell lines, researchers can unravel the molecular mechanisms underlying developmental biology, neurobiology, and cancer progression, thereby gaining insights into how HOOK2 contributes to these complex systems. This makes HOOK2 Gene Knockout Cell Lines invaluable tools in basic research and drug discovery.

Scientifically, these cell lines represent a significant advancement in functional genomics, allowing for the generation of robust experimental models that mimic human disease states. Compared to traditional cell lines, the HOOK2 knockout cells provide a more specific and reliable means to investigate the implications of HOOK2 in pathophysiological contexts.

The unique selling points of the HOOK2 Gene Knockout Cell Lines include their verified genetic modification confirmation and the ease of use in a variety of experimental setups, facilitating reproducibility and saving time during research endeavors. Furthermore, their application extends beyond basic research into potential therapeutic development, offering promising avenues for novel treatments targeting diseases linked to HOOK2 dysregulation.

In conclusion, the HOOK2 Gene Knockout Cell Lines represent a powerful resource for researchers and clinicians aiming to elucidate the mechanisms of gene function and its implications in health and disease. With our company’s longstanding commitment to excellence in the development of advanced biotechnological products and a focus on supporting the scientific community, we provide reliable and innovative tools that can accelerate discovery and enhance understanding in numerous fields of research.

Please note that all services are for research use only. Not intended for any clinical use.

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