Gene: HMBOX1
Official Full Name: homeobox containing 1provided by HGNC
Gene Summary: Enables double-stranded telomeric DNA binding activity; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; telomere maintenance via telomerase; and telomere-telomerase complex assembly. Located in several cellular components, including centrosome; chromosome, telomeric region; and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17079 | HMBOX1 Knockout cell line (HeLa) | Human | HMBOX1 | 1:3~1:6 | Negative | Online Inquiry |
KO17080 | HMBOX1 Knockout cell line (HCT 116) | Human | HMBOX1 | 1:2~1:4 | Negative | Online Inquiry |
KO17081 | HMBOX1 Knockout cell line (HEK293) | Human | HMBOX1 | 1:3~1:6 | Negative | Online Inquiry |
KO17082 | HMBOX1 Knockout cell line (A549) | Human | HMBOX1 | 1:3~1:4 | Negative | Online Inquiry |
HMBOX1 Gene Knockout Cell Lines are advanced biological research tools designed for the comprehensive study of the HMBOX1 gene, which plays a crucial role in various cellular processes, including differentiation and gene regulation. These cell lines have been engineered to lack the HMBOX1 gene, enabling researchers to observe the phenotypic outcomes and biochemical pathways influenced by its absence. Through targeted gene editing techniques, such as CRISPR/Cas9, the HMBOX1 gene is effectively disrupted, resulting in cell lines that serve as invaluable models for understanding the gene's functional contributions.
The primary mechanisms by which these knockout cell lines operate involve the detailed analysis of cellular behaviors and signaling pathways that are altered in the absence of HMBOX1. By providing a controlled environment to study gene function, researchers can investigate its implications in developmental biology, cancer research, and regenerative medicine. Applications range from elucidating the complex regulatory networks of transcription to assessing the response of cells to therapeutic agents, making these tools instrumental in advancing genetic and genomic studies.
One of the key advantages of the HMBOX1 Gene Knockout Cell Lines is their specificity and reproducibility, addressing significant challenges associated with conventional knockout models. While traditional methods may yield inconsistent results or require extensive time and resources, these engineered cell lines offer a streamlined and reliable approach to gene function analysis. They enable researchers to swiftly conduct high-throughput screening and facilitate novel therapeutic discoveries.
For researchers and clinicians focused on genetic mechanisms and disease, the HMBOX1 Gene Knockout Cell Lines provide a potent asset, facilitating insights that may lead to innovative interventions. The depth of understanding gained from utilizing these cell lines can pave the way for breakthroughs in targeted therapies and personalized medicine.
Our company is dedicated to advancing biological research through high-quality cell line models, backed by rigorous scientific expertise and commitment to innovation. We strive to empower researchers with the tools needed to make significant contributions to the field of molecular biology and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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