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HIPK3 Knockout Cell Lines

Gene: HIPK3

Official Full Name: homeodomain interacting protein kinase 3provided by HGNC

Gene Summary: Enables protein serine/threonine kinase activity. Involved in mRNA transcription; negative regulation of apoptotic process; and protein phosphorylation. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04221 HIPK3 Knockout cell line (HeLa) Human HIPK3 1:3~1:6 Negative Online Inquiry
KO04222 HIPK3 Knockout cell line (HCT 116) Human HIPK3 1:2~1:4 Negative Online Inquiry
KO04223 HIPK3 Knockout cell line (HEK293) Human HIPK3 1:3~1:6 Negative Online Inquiry
KO04224 HIPK3 Knockout cell line (A549) Human HIPK3 1:3~1:4 Negative Online Inquiry

Background

HIPK3 Gene Knockout Cell Lines are specialized cell lines in which the HIPK3 gene has been systematically disrupted or deleted, offering researchers a powerful tool for investigating the gene's function in various physiological and pathological processes. HIPK3 (Homeodomain-Interacting Protein Kinase 3) is essential for various cellular processes, including cell proliferation, differentiation, and signal transduction. By using these knockout cell lines, scientists can meticulously dissect the roles of HIPK3 in biological pathways, gaining insights into its contributions to cellular behavior under normal and disease conditions.

The primary function of HIPK3 Gene Knockout Cell Lines lies in their ability to elucidate the gene's specific signaling pathways and molecular interactions. These cell lines serve as a reliable platform for functional assays, enabling the examination of downstream effects on gene expression, protein interactions, and enzymatic activity in the absence of HIPK3. Researchers can utilize these knockout models to simulate conditions of enigmatic diseases or to evaluate the efficacy of therapeutic interventions targeting HIPK3-associated pathways.

The scientific importance of these cell lines extends across various research domains, including cancer biology, neurobiology, and developmental biology, as alterations in HIPK3 have been implicated in several malignancies and developmental disorders. In clinical settings, understanding HIPK3's involvement in disease mechanisms could pave the way for novel therapeutic strategies and biomarkers.

What sets HIPK3 Gene Knockout Cell Lines apart from alternative gene editing tools is their precision and consistency, created using advanced CRISPR/Cas9 technology, ensuring a reliable and reproducible knockout. These cell lines eliminate off-target effects commonly observed in other genetic modification techniques, providing researchers with a clean model system that enhances experimental validity.

Overall, HIPK3 Gene Knockout Cell Lines are invaluable to researchers and clinicians striving to unravel the complexities of gene function and disease. By leveraging our expertise in cutting-edge gene editing technologies, our company offers these high-quality cell lines, ensuring that scientists can confidently push the boundaries of biomedical research to develop effective solutions for healthcare challenges.

Please note that all services are for research use only. Not intended for any clinical use.

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