Gene: HELT
Official Full Name: helt bHLH transcription factorprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; regulation of transcription by RNA polymerase II; and suckling behavior. Predicted to be located in chromatin. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17138 | HELT Knockout cell line (HEK293) | Human | HELT | 1:3~1:6 | Negative | Online Inquiry |
HELT Gene Knockout Cell Lines are advanced biological tools designed for the precise study of gene function through targeted gene deletion. Utilizing CRISPR/Cas9 technology, these cell lines enable researchers to create specific knockouts of the HELT gene, a crucial player in various cellular processes, including differentiation and cell cycle regulation. By disrupting the expression of HELT, scientists can investigate its role in disease mechanisms, particularly in cancer research and developmental biology.
The primary function of HELT Gene Knockout Cell Lines lies in their ability to reveal the physiological and pathological roles of the HELT gene by enabling loss-of-function studies. When the HELT gene is knocked out, researchers can observe changes in cellular behavior, gene expression profiles, and metabolic pathways, providing valuable insights into the gene's function. This knowledge is paramount for understanding the underlying biology of diseases and has significant implications for drug discovery and therapeutic development.
In terms of scientific importance, HELT Gene Knockout Cell Lines serve as essential models in both preclinical research and basic biological studies. They allow for a nuanced examination of gene interactions and cellular responses, facilitating advancements in fields such as regenerative medicine, oncology, and genetic engineering. Unlike traditional gene knockout approaches, which can involve lengthy processes and off-target effects, the precision offered by CRISPR/Cas9 technology significantly reduces these risks, making HELT cell lines a robust choice for thorough investigations.
The advantages of HELT Gene Knockout Cell Lines extend to their ease of use, reproducibility, and ability to generate homogenous cell populations that allow for consistent experimental outcomes. In comparison to other gene editing techniques, our product minimizes the likelihood of secondary mutations, which enhances experimental validity and reliability.
For researchers, clinicians, and biotechnology companies focused on gene function exploration and therapeutic application, HELT Gene Knockout Cell Lines represent a valuable asset. They not only streamline the research process but also help uncover novel therapeutic targets, thus propelling scientific discovery.
Our company brings extensive expertise in developing high-quality biological products backed by rigorous research and development. We are dedicated to equipping the scientific community with the tools necessary to drive innovation and advance understanding within the realms of genetics and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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