Gene: HBQ1
Official Full Name: hemoglobin subunit theta 1provided by HGNC
Gene Summary: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37410 | HBQ1 Knockout cell line (A549) | Human | HBQ1 | 1:3~1:4 | Negative | Online Inquiry |
HBQ1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to lack the expression of the HBQ1 gene. These cell lines serve as vital tools for researchers investigating the functional roles of the HBQ1 gene in various biological processes, including cellular differentiation, growth regulation, and disease pathology. By creating a precise knockout of this gene, researchers can discern its contributions to cellular functions and understand the underlying mechanisms associated with related disorders.
The key function of HBQ1 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function through loss-of-function experiments. The knockout process employs CRISPR-Cas9 technology, which enables targeted gene editing with high specificity and efficiency. This mechanism not only ensures the complete ablation of HBQ1 expression but also provides an opportunity to observe phenotypic changes that may arise from the absence of this gene. Researchers can thus explore pathways influenced by HBQ1 and identify potential therapeutic targets for various diseases, such as cancer and metabolic disorders.
Scientific importance is underscored by the versatility these cell lines offer in both research and clinical settings. In the laboratory, they can be utilized to validate drug targets, investigate gene interactions, and develop personalized medicine approaches based on genetic modifications. Clinically, findings derived from studies using these knockout cell lines can advance our understanding of disease mechanisms, ultimately leading to improved diagnostic and therapeutic strategies.
Compared to traditional cell lines or less sophisticated gene-editing techniques, HBQ1 Gene Knockout Cell Lines provide a more precise and reliable model for studying gene function. Their ability to deliver reproducible results and enhance the reliability of experimental findings makes them indispensable for research laboratories looking to gain deeper insights into the roles of specific genes.
For researchers and clinicians aiming to propel their work forward, these knockout cell lines represent a significant advancement in the pursuit of genetic and molecular research. Our company is committed to providing high-quality biological products that adhere to rigorous scientific standards, ensuring that our clients receive exceptional tools to support their innovative research efforts. By choosing HBQ1 Gene Knockout Cell Lines, you are equipping yourself with a powerful resource that can potentially transform your understanding of gene function in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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