Gene: HBP1
Official Full Name: HMG-box transcription factor 1provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of lipid transport; negative regulation of reactive oxygen species biosynthetic process; and negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Biomarker of osteoarthritis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27953 | HBP1 Knockout cell line (HeLa) | Human | HBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO27954 | HBP1 Knockout cell line (HCT 116) | Human | HBP1 | 1:2~1:4 | Negative | Online Inquiry |
KO27955 | HBP1 Knockout cell line (HEK293) | Human | HBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO27956 | HBP1 Knockout cell line (A549) | Human | HBP1 | 1:3~1:4 | Negative | Online Inquiry |
HBP1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to inactivate the HBP1 gene, which plays a critical role in various biological processes including cell differentiation, growth regulation, and response to stress. By employing cutting-edge CRISPR/Cas9 technology, these cell lines facilitate the study of conserved mechanisms underlying gene regulation and cellular behavior, providing researchers with a powerful tool for dissecting the functional implications of HBP1 loss.
The primary function of HBP1 is to act as a transcriptional repressor, regulating key target genes involved in development and homeostasis. Inactivation of this gene can lead to enhanced cell proliferation or altered differentiation pathways, making knockout models invaluable for investigating the underlying cellular and molecular mechanisms of diseases such as cancer and metabolic disorders. With HBP1 Gene Knockout Cell Lines, researchers can systematically explore the role of HBP1 in various biological contexts, thus paving the way for potential therapeutic insights.
The scientific importance of these cell lines extends to both basic research and translational applications. In basic science, they provide a platform for elucidating gene function in cellular processes. Clinically, they can serve as valuable models for drug discovery, allowing for the evaluation of therapeutic candidates targeting pathways regulated by the HBP1 gene. Compared to traditional knockout methods, HBP1 Gene Knockout Cell Lines offer a more efficient and precise approach with fewer off-target effects, enhancing the reliability of experimental outcomes.
Furthermore, these cell lines come with extensive characterization data, ensuring that users are armed with comprehensive insights into their functionality. As a result of their specificity and reliability, they present a unique advantage over other available models, which may lack the same rigor in genetic validation.
For researchers and clinicians aiming to drive breakthroughs in gene function studies and therapeutic development, HBP1 Gene Knockout Cell Lines represent a significant advancement, encouraging innovative research that can lead to impactful discoveries. Our company specializes in providing high-quality biological products supported by a team of experts committed to facilitating scientific advancements. With our comprehensive portfolio and robust support, we are dedicated to empowering the research community in pushing the boundaries of scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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