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HAVCR1 Knockout Cell Lines

Gene: HAVCR1

Official Full Name: hepatitis A virus cellular receptor 1provided by HGNC

Gene Summary: The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. The protein is a receptor for multiple other viruses, including Ebola virus, Marburg virus, Dengue virus, and Zika virus and is a possible entry factor for SARS-CoV-2 and other coronaviruses. [provided by RefSeq, Sep 2021]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09958 HAVCR1 Knockout cell line (A549) Human HAVCR1 1:3~1:4 Negative Online Inquiry

Background

HAVCR1 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate research into the role of the HAVCR1 gene, which encodes the protein known as Hepatitis A virus cellular receptor 1 (HAVCR1). This product is vital for understanding various biological processes, particularly in the context of viral infections and immune responses. By knocking out the HAVCR1 gene, researchers can investigate the cellular mechanisms that underpin virulence factors, host-pathogen interactions, and potential therapeutic targets, providing insights into diseases such as hepatitis and other viral infections.

The key function of these knockout cell lines lies in their ability to provide a controlled environment for studying the absence of HAVCR1 protein. This allows for the assessment of downstream effects on cell signaling pathways and immune modulation. By utilizing precise CRISPR/Cas9 gene-editing techniques, our HAVCR1 Gene Knockout Cell Lines ensure reproducibility and specificity in experimental setups, making them indispensable tools in molecular biology and virology research.

In clinical settings, these cell lines have significant implications for drug discovery and the development of antiviral therapies. Understanding how the absence of HAVCR1 influences viral replication and immune evasion enhances our ability to design targeted interventions that could improve patient outcomes.

Compared to alternative cell lines that may have variable expression of the HAVCR1 gene, our knockout models provide a consistent, reliable platform for experimentation. Researchers can thus eliminate confounding factors related to gene expression variability, enabling a more accurate assessment of gene function and therapeutic efficacy.

In conclusion, HAVCR1 Gene Knockout Cell Lines represent a critical advancement for researchers and clinicians aiming to explore the complex interactions at the cellular level. Our company is committed to providing high-quality biological products backed by scientific expertise, ensuring that you have the best tools available to drive your research forward with confidence and clarity.

Please note that all services are for research use only. Not intended for any clinical use.

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