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HAPSTR1 Knockout Cell Lines

Gene: HAPSTR1

Official Full Name: HUWE1 associated protein modifying stress responsesprovided by HGNC

Gene Summary: Enables ubiquitin protein ligase binding activity. Involved in negative regulation of signal transduction by p53 class mediator and regulation of cellular response to stress. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17174 HAPSTR1 Knockout cell line (HeLa) Human HAPSTR1 1:3~1:6 Negative Online Inquiry
KO17175 HAPSTR1 Knockout cell line (HCT 116) Human HAPSTR1 1:2~1:4 Negative Online Inquiry
KO17176 HAPSTR1 Knockout cell line (HEK293) Human HAPSTR1 1:3~1:6 Negative Online Inquiry
KO17177 HAPSTR1 Knockout cell line (A549) Human HAPSTR1 1:3~1:4 Negative Online Inquiry

Background

HAPSTR1 Gene Knockout Cell Lines are genetically modified cell lines in which the HAPSTR1 gene has been disrupted through targeted gene knockout techniques. This disruption allows researchers to investigate the functional role of the HAPSTR1 gene in various biological processes and disease mechanisms. By eliminating the expression of this gene, scientists can observe the resulting phenotypic changes and elucidate its involvement in cellular pathways, particularly those related to cellular stress responses and metabolic regulation.

The primary mechanism of action involves the use of CRISPR-Cas9 or similar gene-editing technologies that enable precise modifications to the genome. By specifically targeting HAPSTR1, these cell lines provide invaluable insight into the gene's role in maintaining cellular homeostasis and its contributions to pathophysiological conditions, such as cancer and metabolic disorders. Researchers utilize these cell lines to conduct functional assays, drug screening, and pathway analyses, facilitating a deeper understanding of both basic cell biology and potential therapeutic targets.

The scientific importance of HAPSTR1 Gene Knockout Cell Lines is underscored by their application in both research and clinical settings. They serve as a powerful tool for studying gene function and contribute to drug development by providing relevant biological models that mimic human disease states. As researchers strive to develop targeted therapies, understanding the intricate roles of specific genes like HAPSTR1 becomes crucial.

Compared to conventional cell lines that express the HAPSTR1 gene, these knockout lines offer distinct advantages, including the ability to eliminate background noise in experimental data and the clear observation of phenotypic differences attributable to HAPSTR1 disruption. This specificity enhances experimental reliability and reproducibility, making them a preferred choice for rigorous scientific studies.

By leveraging HAPSTR1 Gene Knockout Cell Lines, researchers and clinicians gain access to a specialized resource that accelerates discoveries in gene function and therapeutic approaches. Investing in these cell lines allows users to explore new avenues of research with confidence in the novelty and utility of the product.

Our company prides itself on providing high-quality biological products backed by in-depth scientific expertise. We are committed to supporting the research community with innovative solutions that advance the understanding and application of genetic technologies.

Please note that all services are for research use only. Not intended for any clinical use.

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