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H3C6 Knockout Cell Lines

Gene: H3C6

Official Full Name: H3 clustered histone 6provided by HGNC

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34244 H3C6 Knockout cell line (HEK293) Human H3C6 1:3~1:6 Negative Online Inquiry
KO34245 H3C6 Knockout cell line (A549) Human H3C6 1:3~1:4 Negative Online Inquiry

Background

H3C6 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology that enables researchers to investigate the role of specific genes in cellular processes. These cell lines are genetically engineered to have a complete knockout of the H3C6 gene, allowing scientists to explore its functional significance in various biological contexts, such as cell differentiation, proliferation, and response to external stimuli.

The primary mechanism of these knockout cell lines involves the use of CRISPR/Cas9 technology, which introduces precise mutations into the H3C6 locus, leading to the loss of gene function. This targeted approach not only enhances the reliability of experimental data but also facilitates the study of gene interactions and pathways with unmatched specificity. By utilizing H3C6 Gene Knockout Cell Lines, researchers can gain deeper insights into the molecular mechanisms underlying diseases, paving the way for the development of novel therapeutic strategies.

The scientific importance of H3C6 Gene Knockout Cell Lines is underscored by their potential applications in fundamental research and translational medicine. They serve as model systems for understanding diseases such as cancer, neurodegenerative disorders, and metabolic diseases, making them invaluable in both academic and clinical settings. These cell lines allow for high-throughput screening, which is critical for drug development and biomarker discovery.

One significant advantage of H3C6 Gene Knockout Cell Lines is their precision and reproducibility compared to traditional gene knockdown techniques. Unlike RNA interference, which can yield off-target effects, the knockout strategy ensures a complete loss of function, providing clearer insights into the gene's role. Moreover, these cell lines can be easily adapted for various assays, enabling versatile experimental designs.

Researchers and clinicians can significantly benefit from employing H3C6 Gene Knockout Cell Lines due to their robustness and the insights they provide into gene functionality. This product not only enhances the accuracy of biological studies but also fosters innovation in therapeutic approaches.

At our company, we pride ourselves on our expertise in developing high-quality biological products tailored for cutting-edge research. Our commitment to advancing scientific discovery ensures that H3C6 Gene Knockout Cell Lines meet the highest standards, ultimately aiding researchers in unlocking the complexities of gene function and their implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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