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GTSF1 Knockout Cell Lines

Gene: GTSF1

Official Full Name: gametocyte specific factor 1provided by HGNC

Gene Summary: Enables tRNA binding activity. Predicted to be involved in piRNA-mediated gene silencing by mRNA destabilization and secondary piRNA processing. Predicted to be located in cytoplasm. Predicted to be active in piP-body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29443 GTSF1 Knockout cell line (HCT 116) Human GTSF1 1:2~1:4 Negative Online Inquiry

Background

GTSF1 Gene Knockout Cell Lines are genetically engineered cell lines in which the GTSF1 gene has been systematically inactivated or "knocked out." This process involves the targeted use of CRISPR-Cas9 or other gene editing technologies to remove or disrupt the GTSF1 gene, allowing researchers to study the gene's function and its role in various biological processes. GTSF1, known for its involvement in cellular stress responses, germ cell development, and regulation of stem cell properties, makes these knockout cell lines particularly valuable for understanding fundamental mechanisms of disease and cellular behavior.

The fundamental mechanism behind the GTSF1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment to study the biological implications of GTSF1 deficiency. Researchers can analyze the resulting phenotypic changes, alterations in cellular signaling pathways, and impacts on gene expression profiles. This approach facilitates insights into diseases where GTSF1 may play a critical role, such as infertility or certain cancers.

From a scientific standpoint, these cell lines are essential tools in both research and clinical applications. They can be utilized for drug development, toxicity studies, and the exploration of cellular responses to stressors or therapeutic agents, thereby contributing significantly to the fields of molecular biology, genetics, and pharmacology.

One of the unique advantages of GTSF1 Gene Knockout Cell Lines over traditional cell lines is their specific focus on the GTSF1 pathway, which allows for precise investigations that are unattainable with standard cell lines. Additionally, they offer high reproducibility and versatility across various experimental conditions, making them suitable for a broad range of studies. Their potential to unveil critical insights into disease mechanisms distinguishes them from other genetic models.

For researchers and clinicians seeking to understand the implications of GTSF1 in health and disease, these knockout cell lines represent not only the forefront of genetic research but also the opportunity to develop targeted therapies. By providing a robust platform for discovery, GTSF1 Gene Knockout Cell Lines can pave the way for advancements in regenerative medicine, cancer treatment, and reproductive health.

With a commitment to excellence in genetic modification technologies and cell line development, our company stands at the cutting edge of biotechnological innovations, ensuring that researchers have access to high-quality, rigorously validated cellular models that support their scientific and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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