Gene: GSE1
Official Full Name: Gse1 coiled-coil proteinprovided by HGNC
Gene Summary: This gene encodes a proline-rich protein with coiled coil domains that may be a subunit of a BRAF35-HDAC (BHC) histone deacetylase complex. This gene may function as an oncogene in breast cancer and enhanced expression of the encoded protein has been observed in breast cancer patients. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05982 | GSE1 Knockout cell line (HeLa) | Human | GSE1 | 1:3~1:6 | Negative | Online Inquiry |
KO05983 | GSE1 Knockout cell line (HCT 116) | Human | GSE1 | 1:2~1:4 | Negative | Online Inquiry |
KO05984 | GSE1 Knockout cell line (HEK293) | Human | GSE1 | 1:3~1:6 | Negative | Online Inquiry |
KO05985 | GSE1 Knockout cell line (A549) | Human | GSE1 | 1:3~1:4 | Negative | Online Inquiry |
GSE1 Gene Knockout Cell Lines are advanced cellular models specifically engineered to study the functional role of the GSE1 gene in various biological processes. These cell lines have undergone precise genomic editing to entirely delete the GSE1 gene, allowing researchers to assess the downstream effects of this genetic alteration on cellular behavior, signaling pathways, and overall phenotype.
The core function of GSE1 Gene Knockout Cell Lines lies in their ability to simulate the loss-of-function scenarios that researchers frequently encounter in disease models, particularly in cancer and developmental biology. By elucidating the impact of GSE1 gene deletion, scientists can gain insights into its contribution to cellular processes such as proliferation, differentiation, and apoptosis. This mechanistic understanding is critical for identifying potential therapeutic targets and for developing new intervention strategies.
Scientifically, the significance of GSE1 Gene Knockout Cell Lines is underscored by their utility in both basic and applied research settings. In clinical research, these cell lines can serve as valuable platforms for drug screening and validation, assessing how therapies interact with GSE1-deficient cells. Potential applications also extend into the study of genetic disorders, providing a cellular context to understanding disease mechanisms linked to GSE1 dysfunction.
What differentiates GSE1 Gene Knockout Cell Lines from traditional research models is their genetically modified state—offering a higher degree of specificity and predictive accuracy in experimental outcomes. Unlike unmodified cell lines, which may exhibit heterogeneous responses due to polygenic interactions, GSE1 knockout variants enable researchers to attribute observed phenotypic changes directly to the absence of the GSE1 gene.
Researchers and clinicians will find significant value in these specialized cell lines as they streamline the process of hypothesis testing and facilitate discoveries that are essential for advancing scientific knowledge and clinical practice. The development and provision of GSE1 Gene Knockout Cell Lines are backed by our company’s robust expertise in genetic engineering and cell biology, ensuring that users receive high-quality products that meet the rigorous demands of modern research.
Please note that all services are for research use only. Not intended for any clinical use.
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