Gene: GPSM2
Official Full Name: G protein signaling modulator 2provided by HGNC
Gene Summary: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26975 | GPSM2 Knockout cell line (HeLa) | Human | GPSM2 | 1:3~1:6 | Negative | Online Inquiry |
KO26976 | GPSM2 Knockout cell line (HCT 116) | Human | GPSM2 | 1:2~1:4 | Negative | Online Inquiry |
KO26977 | GPSM2 Knockout cell line (HEK293) | Human | GPSM2 | 1:3~1:6 | Negative | Online Inquiry |
KO26978 | GPSM2 Knockout cell line (A549) | Human | GPSM2 | 1:3~1:4 | Negative | Online Inquiry |
GPSM2 Gene Knockout Cell Lines are engineered cellular models that have been specifically designed to study the role of the GPSM2 gene in various biological processes. By utilizing CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the GPSM2 gene, leading to the disruption of its normal biological functions. This precise alteration allows researchers to investigate the downstream effects of GPSM2 loss, thereby elucidating its role in cellular signaling pathways, immune response mechanisms, and development processes.
The unique functionality of these knockout cell lines offers a robust research platform for understanding the molecular mechanisms underlying health and disease. By providing insights into the regulatory roles of GPSM2, researchers can explore its implications in diverse fields such as cancer biology, neurobiology, and immunology. The availability of these genetically modified cell lines enables the development of targeted therapeutic strategies, potentially leading to breakthroughs in clinical settings.
Compared to alternative models, such as wild-type cell lines or less efficient gene-silencing techniques, GPSM2 Gene Knockout Cell Lines deliver a more definitive and reproducible approach to gene function analysis. Their specificity allows for a clearer interpretation of experimental results, reducing confounding variables that could arise from incomplete gene knockdown strategies.
Researchers and clinicians benefit significantly from utilizing these cell lines due to the wealth of knowledge they unlock pertaining to GPSM2, a gene implicated in various pathologies. Additionally, our expertise in genetic engineering and cell line development ensures that customers receive high-quality, validated products with consistent performance.
By choosing GPSM2 Gene Knockout Cell Lines, users invest in a powerful tool for advancing their scientific inquiries, backed by our company’s commitment to excellence in biotechnological products.
Please note that all services are for research use only. Not intended for any clinical use.
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