Gene: GPD1L
Official Full Name: glycerol-3-phosphate dehydrogenase 1 likeprovided by HGNC
Gene Summary: The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02122 | GPD1L Knockout cell line (HeLa) | Human | GPD1L | 1:3~1:6 | Negative | Online Inquiry |
KO02123 | GPD1L Knockout cell line (HCT 116) | Human | GPD1L | 1:2~1:4 | Negative | Online Inquiry |
KO02124 | GPD1L Knockout cell line (HEK293) | Human | GPD1L | 1:3~1:6 | Negative | Online Inquiry |
KO02125 | GPD1L Knockout cell line (A549) | Human | GPD1L | 1:3~1:4 | Negative | Online Inquiry |
GPD1L Gene Knockout Cell Lines are genetically modified cell lines designed to lack the expression of the glycerol-3-phosphate dehydrogenase 1-like (GPD1L) gene. This product enables the study of GPD1L’s functional roles in cellular metabolism, cardiac physiology, and various signaling pathways. By utilizing advanced CRISPR-Cas9 gene editing technology, these knockout cell lines serve as vital tools for researchers exploring the implications of GPD1L deficiency in disease models, particularly in metabolic disorders and cardiac dysfunctions.
The primary function of the GPD1L Gene Knockout Cell Lines is to facilitate rigorous investigations into the mechanistic pathways influenced by the GPD1L gene. This cell line permits researchers to observe alterations in metabolic profiles, energy homeostasis, and cellular stress responses resulting from GPD1L suppression. By comparing these knockout cells to wild-type counterparts, scientists can elucidate the gene's contribution to physiological functions, thereby enhancing overall understanding of its role in health and disease.
In the context of scientific research and clinical applications, GPD1L Gene Knockout Cell Lines are invaluable. They promote insights into the underlying mechanisms of related diseases, potentially leading to novel therapeutic strategies. Their specificity facilitates a detailed understanding of the gene's impact, which is crucial in developing targeted interventions in cardiovascular and metabolic conditions.
What sets these cell lines apart from existing alternatives is their precision and reliability. Each line is thoroughly validated for gene knockout efficiency and characterized for consistency in experimental results, ensuring reproducibility. Moreover, the ease of use in various culture systems makes them highly adaptable for diverse experimental settings.
These knockout cell lines represent a significant advancement in genetic research tools, enabling scientists to pursue groundbreaking discoveries in the study of GPD1L. Researchers and clinicians stand to benefit immensely from their use, making strides towards innovative treatments for complex diseases. By offering robust, well-characterized cell lines, our company underlines its commitment to advancing biological research through high-quality, innovative products tailored to contemporary scientific needs.
Please note that all services are for research use only. Not intended for any clinical use.
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