Gene: GPC4
Official Full Name: glypican 4provided by HGNC
Gene Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04252 | GPC4 Knockout cell line (HCT 116) | Human | GPC4 | 1:2~1:4 | Negative | Online Inquiry |
KO04253 | GPC4 Knockout cell line (HEK293) | Human | GPC4 | 1:3~1:6 | Negative | Online Inquiry |
GPC4 Gene Knockout Cell Lines are genetically engineered cell models in which the Glypican-4 (GPC4) gene has been inactivated or "knocked out." This innovative product is designed to facilitate the study of the role of GPC4 in various biological processes, particularly in the context of cancer research, developmental biology, and cellular signaling. GPC4 is a member of the glypican family of heparan sulfate proteoglycans, which are implicated in the modulation of growth factor signaling, cell proliferation, and tumorigenesis.
These cell lines function through the complete absence of GPC4 expression, allowing researchers to elucidate the gene's contributions to cellular pathways and its involvement in pathological conditions. By employing CRISPR-Cas9 technology or other gene editing methods, we ensure a robust knockout effect, enabling comprehensive functional studies and drug response assays. The GPC4 Gene Knockout Cell Lines serve as invaluable tools for understanding the molecular mechanisms underlying various diseases, offering insights that can translate into therapeutic advancements.
The scientific importance of these cell lines lies in their application across research fields, including cancer biology, regenerative medicine, and developmental studies. Their ability to provide a precise model for examining pathophysiology makes them essential for hypothesis-driven research and the development of targeted therapies. Compared to traditional knockout models, our GPC4 Gene Knockout Cell Lines offer consistent and reproducible results, reducing variability, and enhancing the reliability of experimental outcomes.
Researchers and clinicians benefit from our product's unique selling points, such as easy cultivation, high transfection efficiency, and compatibility with various assays, including high-throughput screening and gene expression analysis. This cultivates an environment conducive to innovative discoveries and accelerates the advancement of translational research.
At [Your Company Name], we pride ourselves on our expertise in developing high-quality genetic models that support the scientific community in their quest to unlock the mysteries of gene function. Our GPC4 Gene Knockout Cell Lines embody our commitment to precision and excellence in biotechnology, providing researchers with the tools necessary to drive scientific discovery forward.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.