Gene: GOLT1B
Official Full Name: golgi transport 1Bprovided by HGNC
Gene Summary: Involved in positive regulation of canonical NF-kappaB signal transduction. Located in endoplasmic reticulum. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07370 | GOLT1B Knockout cell line (HeLa) | Human | GOLT1B | 1:3~1:6 | Negative | Online Inquiry |
KO07371 | GOLT1B Knockout cell line (HCT 116) | Human | GOLT1B | 1:2~1:4 | Negative | Online Inquiry |
KO07372 | GOLT1B Knockout cell line (HEK293) | Human | GOLT1B | 1:3~1:6 | Negative | Online Inquiry |
KO07373 | GOLT1B Knockout cell line (A549) | Human | GOLT1B | 1:3~1:4 | Negative | Online Inquiry |
GOLT1B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to provide researchers with a powerful tool for studying the functional role of the GOLT1B gene in various cellular processes. The GOLT1B gene is implicated in critical mechanisms such as glycosylation and the regulation of endoplasmic reticulum (ER) functions, making it significant for understanding not just basic cellular biology but also disease states related to protein misfolding and trafficking.
These knockout cell lines utilize CRISPR/Cas9 technology to effectively disrupt the GOLT1B gene, allowing for precise examination of cellular behavior in the absence of this gene's activity. By eliminating GOLT1B, researchers can investigate its impact on cellular pathways such as protein export, the unfolded protein response, and overall cellular stress response mechanisms. This creates opportunities to explore novel therapeutic targets for diseases ranging from cancer to neurodegenerative disorders.
The scientific importance of GOLT1B Gene Knockout Cell Lines lies in their ability to yield insights that can lead to innovative treatments and diagnostic tools. Unlike traditional methods of gene silencing, these knockout lines offer a stable, irreversible alteration that enables long-term studies of gene function and its downstream effects, enhancing the reproducibility and reliability of experimental results.
One of the main advantages of these knockout cell lines over competitors is their ease of use and customization, allowing researchers to tailor their investigations to specific experimental needs. Additionally, the purity and specificity of our knockout models minimize off-target effects, which is often a concern with other gene-editing techniques.
For researchers and clinicians aiming to probe the complex roles of the GOLT1B gene in physiology and pathology, GOLT1B Gene Knockout Cell Lines represent an invaluable resource. They facilitate groundbreaking studies that can lead to significant advancements in our understanding of cellular mechanisms and pathology.
Our commitment to providing high-quality biological products, backed by extensive research and quality control, ensures that our GOLT1B Gene Knockout Cell Lines meet the rigorous standards needed in modern biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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