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GOLM1 Knockout Cell Lines

Gene: GOLM1

Official Full Name: golgi membrane protein 1provided by HGNC

Gene Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Sep 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03806 GOLM1 Knockout cell line (HeLa) Human GOLM1 1:3~1:6 Negative Online Inquiry
KO03807 GOLM1 Knockout cell line (HCT 116) Human GOLM1 1:2~1:4 Negative Online Inquiry
KO03808 GOLM1 Knockout cell line (HEK293) Human GOLM1 1:3~1:6 Negative Online Inquiry
KO03809 GOLM1 Knockout cell line (A549) Human GOLM1 1:3~1:4 Negative Online Inquiry

Background

GOLM1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the Golgi membrane protein 1 (GOLM1) and its role in various biological processes. These cell lines are created through precise gene editing techniques, such as CRISPR-Cas9, which effectively inactivate the GOLM1 gene, allowing researchers to observe the resultant phenotypic changes and cellular behaviors in a controlled environment.

The primary function of GOLM1 is associated with the Golgi apparatus, where it plays a critical role in glycosylation processes and protein trafficking. By utilizing these knockout cell lines, scientists can investigate the pathways and networks influenced by GOLM1, providing insights into its involvement in cellular signaling, Golgi structure maintenance, and its potential link to disease states, particularly in cancer and neurodegenerative disorders. In clinical research settings, the knockout models serve as vital tools for drug discovery and development, enabling the identification of therapeutic targets and the evaluation of drug efficacy.

What sets GOLM1 Gene Knockout Cell Lines apart from traditional cell models is their specificity and the enhanced reliability of results. While conventional methods may lack precise control over gene expression, these knockout lines yield consistent and reproducible data, allowing for more robust conclusions. Furthermore, they significantly reduce background noise that can obscure results when studying gene function in wild-type cells.

For researchers and clinicians, these cell lines represent a powerful resource for unraveling the complex biological roles of GOLM1 and translating findings into practical therapeutic applications. Their adoption can significantly enhance experimental efficiency, potentially leading to faster breakthroughs in understanding diseases influenced by this protein.

Our company is dedicated to providing high-quality biological products, leveraging cutting-edge genomics technologies and extensive expertise in molecular biology to empower researchers in their quest for groundbreaking discoveries. With our GOLM1 Gene Knockout Cell Lines, you gain access to a uniquely valuable platform that supports innovative research and contributes to advancements in health and disease understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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