Gene: GNG5B
Official Full Name: G protein subunit gamma 5Bprovided by HGNC
Gene Summary: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17355 | GNG5B Knockout cell line (HeLa) | Human | GNG5B | 1:3~1:6 | Negative | Online Inquiry |
KO17356 | GNG5B Knockout cell line (HCT 116) | Human | GNG5B | 1:2~1:4 | Negative | Online Inquiry |
KO17357 | GNG5B Knockout cell line (HEK293) | Human | GNG5B | 1:3~1:6 | Negative | Online Inquiry |
KO17358 | GNG5B Knockout cell line (A549) | Human | GNG5B | 1:3~1:4 | Negative | Online Inquiry |
GNG5B Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to lack the GNG5B gene, which encodes a key protein involved in G-protein signaling pathways. This innovative tool enables researchers to study the functional roles of GNG5B and its implications in various biological processes, including cellular signaling, receptor-mediated actions, and potential pathophysiological conditions.
The primary function of GNG5B knockout cell lines is to provide a controlled environment for elucidating the effects of GNG5B loss on cellular behavior. By using CRISPR/Cas9 technology for precise gene editing, these knockout cell lines allow for the investigation of GNG5B's role in signal transduction, enabling detailed studies on how its absence affects downstream signaling pathways and cellular responses. This makes them invaluable tools for dissecting the complexities of G-protein coupled receptor (GPCR) signaling and its broader ramifications in health and disease.
The scientific importance of GNG5B knockout cell lines extends to various research applications, including pharmacological studies, functional genomics, and the exploration of therapeutic targets for conditions such as cancer and metabolic disorders. In clinical settings, understanding the signaling mechanisms associated with GNG5B could lead to the development of novel therapies aimed at modulating GPCR functions and addressing related pathologies.
One of the unique advantages of our GNG5B knockout cell lines is their stringent validation and characterization, ensuring high specificity and reproducibility. This level of quality control sets our product apart from alternatives that may not offer the same reliability in experimental outcomes. Additionally, these cell lines come with detailed documentation and support, which accelerates the research process by providing users with essential background information and guidance.
For researchers and clinicians aiming to refine their understanding of GNG5B's role in various biological contexts, these knockout cell lines offer a valuable resource that fosters innovation and discovery. By utilizing our GNG5B gene knockout cell lines, users can confidently explore new avenues of research with the potential for meaningful impacts on the field of biomedical science.
Our company prides itself on its expertise in genetic engineering and cell line development, positioning us as a trusted partner in advancing scientific research. With a commitment to quality and customer support, we offer an extensive range of biological products that cater to the diverse needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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