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GMFG Knockout Cell Lines

Gene: GMFG

Official Full Name: glia maturation factor gammaprovided by HGNC

Gene Summary: Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in extracellular region; ficolin-1-rich granule lumen; and secretory granule lumen. Predicted to be active in cortical actin cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33148 GMFG Knockout cell line (HeLa) Human GMFG 1:3~1:6 Negative Online Inquiry

Background

GMFG Gene Knockout Cell Lines are specialized cellular models in which the GMFG gene, crucial for various cellular processes, has been systematically disrupted to study its functional role. These cell lines are developed using cutting-edge CRISPR-Cas9 gene-editing technology, enabling precise and efficient knockout of the GMFG gene. This targeted approach allows for the investigation of gene function and the elucidation of pathways influenced by GMFG in both physiological and pathological contexts.

The key function of GMFG is to modulate the actin cytoskeleton, playing a significant role in cell migration, proliferation, and immune responses. By creating GMFG-deficient cell lines, researchers can observe phenotypic changes that occur due to the loss of this gene, offering insights into its role in processes such as tumorigenesis, neurodegenerative diseases, and immune system function.

The scientific importance of GMFG Gene Knockout Cell Lines lies in their applications across various fields of research, including cancer biology, developmental biology, and immunology. They facilitate high-throughput studies to decipher the molecular mechanisms of action of GMFG and its involvement in disease pathology, thereby propelling the development of potential therapeutic strategies.

What sets our GMFG Gene Knockout Cell Lines apart is not only their high fidelity and reproducibility but also the extensive characterization provided with each cell line. This product is validated with robust quality control standards and is offered with detailed protocols and data sheets that guide researchers in functional assays and subsequent experiments.

For researchers and clinicians seeking to explore cellular mechanisms or develop targeted interventions, our GMFG Gene Knockout Cell Lines represent an invaluable tool. By equipping users with reliable and cutting-edge resources, our company, with years of expertise in biological products, ensures that you have the support needed to advance your research and clinical goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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