Gene: GLMN
Official Full Name: glomulin, FKBP associated proteinprovided by HGNC
Gene Summary: This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Multiple splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31163 | GLMN Knockout cell line (HeLa) | Human | GLMN | 1:3~1:6 | Negative | Online Inquiry |
KO31164 | GLMN Knockout cell line (HCT 116) | Human | GLMN | 1:2~1:4 | Negative | Online Inquiry |
KO31165 | GLMN Knockout cell line (HEK293) | Human | GLMN | 1:3~1:6 | Negative | Online Inquiry |
KO31166 | GLMN Knockout cell line (A549) | Human | GLMN | 1:3~1:4 | Negative | Online Inquiry |
GLMN Gene Knockout Cell Lines are highly specialized cellular models created through targeted gene disruption techniques, specifically designed to study the biological functions of the GLMN gene, which has been implicated in various cellular processes, including cell proliferation and stress responses. These cell lines provide researchers with invaluable tools for understanding the role of GLMN in cellular pathways, disease mechanisms, and potential therapeutic targets.
The GLMN Gene Knockout Cell Lines operate through CRISPR-Cas9 technology, which ensures precise editing of the genome, facilitating the complete inactivation of the GLMN gene. By eliminating this specific gene, researchers can investigate the resulting phenotypic and molecular changes, providing insights into gene functionalities and related biological phenomena. Mechanistically, these knockout models allow for the dual exploration of loss-of-function effects and compensation by other cellular pathways, thus enhancing the understanding of cellular dynamics in both normal and pathological states.
In terms of scientific importance, these knockout cell lines have broad applications in fields such as cancer research, developmental biology, and genetic disorders. They serve as foundational models to test hypotheses related to gene function, helping to elucidate the role of GLMN in various disease states and its potential as a therapeutic target.
The unique selling points of GLMN Gene Knockout Cell Lines lie in their specificity, reproducibility, and robustness. Unlike traditional methods that may lead to off-target effects, the precision of CRISPR technology ensures that the KO model reflects the true biological consequences of the gene's loss. Moreover, these cell lines are optimized for growth and handling, allowing for streamlined experimental procedures compared to more cumbersome alternatives.
For researchers and clinicians alike, GLMN Gene Knockout Cell Lines present a significant opportunity to accelerate their studies and develop innovative therapeutic strategies. With access to such a refined experimental tool, users can generate reliable data and gain a deeper understanding of the genetic underpinnings of diseases.
As a leader in biotechnology, our company is dedicated to providing high-quality biological products, including meticulously validated gene knockout models. Our expertise ensures that customers receive tools tailored for excellence in research and clinical applications, enabling pioneering discoveries that can translate into transformative healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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