Gene: GJC1
Official Full Name: gap junction protein gamma 1provided by HGNC
Gene Summary: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03093 | GJC1 Knockout cell line (HeLa) | Human | GJC1 | 1:3~1:6 | Negative | Online Inquiry |
KO03094 | GJC1 Knockout cell line (HCT 116) | Human | GJC1 | 1:2~1:4 | Negative | Online Inquiry |
KO03095 | GJC1 Knockout cell line (HEK293) | Human | GJC1 | 1:3~1:6 | Negative | Online Inquiry |
KO03096 | GJC1 Knockout cell line (A549) | Human | GJC1 | 1:3~1:4 | Negative | Online Inquiry |
GJC1 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the in-depth study of the GJC1 gene and its associated pathways. These cell lines are created using precise gene editing techniques to eliminate the expression of the GJC1 gene, allowing researchers to investigate its role in various biological processes and disease mechanisms without the interference of functional gene products.
The key functionality of GJC1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment to dissect the implications of GJC1 deficiency. The GJC1 gene encodes a protein involved in cellular communication and gap junction formation, which is crucial in maintaining homeostasis in tissues such as the heart and nervous system. By analyzing these knockout cell lines, researchers can elucidate the impact of GJC1 on cell signaling, tissue repair, and physiological responses to stressors, thereby opening avenues for the exploration of conditions such as cardiac arrhythmias and neurological disorders.
Scientifically, GJC1 Gene Knockout Cell Lines hold significant applications in both research and clinical settings. They serve as invaluable tools for drug discovery, disease modeling, and functional genomics studies. The knockout models allow for the validation of therapeutic targets and the assessment of novel compounds' efficacy, particularly in diseases linked to gap junction dysfunction.
One of the primary advantages of using GJC1 Gene Knockout Cell Lines is their specificity and reliability over alternative models, such as transient knockdowns or non-targeted approaches, which can yield variable and non-reproducible results. These knockout lines provide stability and consistency, allowing for more robust experimental designs and reproducible outcomes. Furthermore, the profound insights gained from studying these cells contribute to the understanding of not just GJC1-related pathologies, but also the broader implications of intercellular communication.
In conclusion, GJC1 Gene Knockout Cell Lines represent a pivotal resource for scientists and clinicians aiming to explore the complexities of genetic regulation and disease mechanisms. By providing high-fidelity models that enhance research accuracy and relevance, our product empowers the scientific community to make informed breakthroughs. With years of expertise in biotechnological development and a commitment to advancing health science, our company stands at the forefront of providing high-quality biological products tailored to accelerate your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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