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GJB5 Knockout Cell Lines

Gene: GJB5

Official Full Name: gap junction protein beta 5provided by HGNC

Gene Summary: This gene encodes a member of the beta-type (group I) connexin family. The encoded protein is a gap junction protein involved in intercellular communication related to epidermal differentiation and environmental sensing. This gene has been linked to non-small cell lung cancer. [provided by RefSeq, Nov 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37654 GJB5 Knockout cell line (HCT 116) Human GJB5 1:2~1:4 Negative Online Inquiry

Background

GJB5 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the function of the GJB5 gene, a critical component of gap junctions responsible for intercellular communication. These knockout cell lines have undergone precise genetic manipulation to disrupt the expression of GJB5, providing researchers with a powerful tool to elucidate the gene's role in cellular processes and its implications in various diseases.

The primary function of the GJB5 Gene Knockout Cell Lines lies in their ability to help scientists investigate the phenotypic consequences of GJB5 dysfunction. By examining these cells, researchers can discern the cellular mechanisms that underpin conditions such as hearing loss and skin disorders, thereby advancing our understanding of gap junction-related pathologies. This tool enables the exploration of gene-environment interactions, drug responses, and cellular communication pathways that are vital for both basic research and translational studies.

In clinical and research settings, these knockout cell lines are essential for the development of gene therapies and the testing of novel pharmacological agents aimed at restoring GJB5 function. Their use can accelerate the identification of therapeutic targets and facilitate the design of personalized medicine approaches that may significantly improve patient outcomes.

One of the standout advantages of using GJB5 Gene Knockout Cell Lines over traditional models is their specificity and precision. Unlike non-specific in vitro systems, these cell lines provide a directed approach for studying the consequences of GJB5 deletion, allowing for more reliable and reproducible results. Additionally, the ability to easily generate and maintain these cell lines streamlines experimental workflows.

For researchers and clinicians focused on genetic and cellular pathology, GJB5 Gene Knockout Cell Lines offer an unparalleled opportunity to delve deeply into the molecular intricacies that govern health and disease. This product not only enhances scientific understanding but also drives innovation in therapeutic strategies.

Our company is recognized for its commitment to providing high-quality biological products that support groundbreaking research. With a wealth of expertise in genetic manipulation and cellular biology, we are dedicated to empowering researchers with the tools they need to advance their work and unleash new possibilities in the study of genetics and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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