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GIT1 Knockout Cell Lines

Gene: GIT1

Official Full Name: GIT ArfGAP 1provided by HGNC

Gene Summary: Enables gamma-tubulin binding activity. Involved in positive regulation of microtubule nucleation and regulation of cytokinesis. Located in several cellular components, including focal adhesion; microtubule cytoskeleton; and mitochondrion. Implicated in attention deficit hyperactivity disorder. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27295 GIT1 Knockout cell line (HeLa) Human GIT1 1:3~1:6 Negative Online Inquiry
KO27296 GIT1 Knockout cell line (HCT 116) Human GIT1 1:2~1:4 Negative Online Inquiry
KO27297 GIT1 Knockout cell line (HEK293) Human GIT1 1:3~1:6 Negative Online Inquiry
KO27298 GIT1 Knockout cell line (A549) Human GIT1 1:3~1:4 Negative Online Inquiry

Background

GIT1 Gene Knockout Cell Lines are genetically modified cell lines created through the targeted deletion of the GIT1 (G-protein coupled receptor kinase-interacting protein 1) gene. This innovative product serves as a critical tool for researchers investigating the functional role of GIT1 in various cellular processes, including cell signaling, cytoskeletal dynamics, and cellular adhesion. By disrupting the expression of this essential gene, scientists can explore the implications of GIT1 absence in physiological and pathological contexts, such as cancer metastasis and neuronal signaling.

The key functionality of GIT1 Gene Knockout Cell Lines lies in their ability to facilitate in-depth studies of gene function and regulation. These cell lines exhibit altered behaviors that can be quantitatively measured, allowing researchers to analyze changes in cellular responses to stimuli. The knockout mechanism results in the loss of GIT1 protein expression, leading to various downstream effects on cell motility, morphological changes, and interaction with various signaling pathways. Such insights are invaluable for elucidating protein networks and developing therapeutic strategies targeting the GIT1 pathway.

The scientific importance of GIT1 Gene Knockout Cell Lines extends into both basic and applied research. For instance, in the realm of cancer biology, understanding GIT1's role can shed light on how tumor cells migrate and invade surrounding tissues. In neuroscience, elucidating GIT1 function may reveal critical pathways involved in synaptic plasticity and neurological disorders. These applications underscore the relevance of GIT1 knockouts in advancing therapeutic interventions.

What sets our GIT1 Gene Knockout Cell Lines apart from alternatives is their stringent validation and characterization, ensuring reproducibility and reliability in experimental results. Our cell lines are rigorously tested for gene deletion efficiency and functionality, enabling researchers to obtain accurate and meaningful data.

For researchers and clinicians alike, the GIT1 Gene Knockout Cell Lines offer a compelling opportunity to probe the complexities of gene function and its implications for health and disease. By using this product, users can benefit from a reliable tool that accelerates advancements in their studies and paves the way for novel therapeutic strategies.

At our company, we pride ourselves on our commitment to scientific excellence and innovation in providing high-quality biological products. Leveraging our expertise in genetic engineering and cell biology, we ensure that our offerings meet the rigorous demands of modern research and clinical applications, positioning us as a leader in the field of biochemical tools and resources.

Please note that all services are for research use only. Not intended for any clinical use.

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