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GDPD1 Knockout Cell Lines

Gene: GDPD1

Official Full Name: glycerophosphodiester phosphodiesterase domain containing 1provided by HGNC

Gene Summary: This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. The encoded protein is localized to the cytoplasm and concentrates near the perinuclear region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17413 GDPD1 Knockout cell line (HeLa) Human GDPD1 1:3~1:6 Negative Online Inquiry
KO17414 GDPD1 Knockout cell line (HCT 116) Human GDPD1 1:2~1:4 Negative Online Inquiry
KO17415 GDPD1 Knockout cell line (HEK293) Human GDPD1 1:3~1:6 Negative Online Inquiry
KO17416 GDPD1 Knockout cell line (A549) Human GDPD1 1:3~1:4 Negative Online Inquiry

Background

GDPD1 Gene Knockout Cell Lines are genetically modified cellular models specifically engineered to lack expression of the GDPD1 gene, a crucial component implicated in various biological processes including lipid metabolism and cell signaling pathways. These cell lines serve as indispensable tools in the study of the physiological roles of GDPD1 and its association with diseases such as cancer and neurodegenerative disorders. By observing the functional consequences of GDPD1 gene disruption, researchers can elucidate the underpinnings of its biological role, thereby advancing understanding of related pathological mechanisms.

The primary function of GDPD1, a glycerophosphodiester phosphodiesterase, includes the hydrolysis of glycerophosphodiesters into their corresponding alcohols and inorganic phosphate. This reaction is pivotal for modulating lipid signaling and membrane dynamics. By utilizing the GDPD1 Gene Knockout Cell Lines, researchers can investigate the biochemical cascades that occur in the absence of GDPD1, assess the resulting phenotypic changes, and explore downstream signaling pathways that are critical for cell homeostasis and communication.

In both research and clinical settings, these knockout cell lines have significant applications, particularly in pharmacology and toxicology studies, where understanding the functional impact of gene loss can inform therapeutic strategies. Moreover, the ability to personalize investigations into GDPD1’s cellular functions makes these models invaluable for translational research, including drug development and targeted therapies.

Moreover, GDPD1 Gene Knockout Cell Lines stand out from alternative models due to their precise genetic modification, which offers a higher fidelity in studying the gene’s specific contributions to cellular functions without the confounding factors present in wild-type cell lines. Additionally, their availability in various tissue-specific backgrounds enhances their versatility, purposefully meeting the diverse needs of researchers working in molecular biology, cellular physiology, and therapeutic developments.

These cell lines provide researchers and clinicians with a powerful platform to unlock the mysteries of lipid homeostasis and disease progression. Our company is dedicated to advancing the field with our expertly engineered biological products, ensuring high-quality resources that foster innovative discoveries and groundbreaking progress in scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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