Gene: GCC1
Official Full Name: GRIP and coiled-coil domain containing 1provided by HGNC
Gene Summary: The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17421 | GCC1 Knockout cell line (HeLa) | Human | GCC1 | 1:3~1:6 | Negative | Online Inquiry |
KO17422 | GCC1 Knockout cell line (HCT 116) | Human | GCC1 | 1:2~1:4 | Negative | Online Inquiry |
KO17423 | GCC1 Knockout cell line (HEK293) | Human | GCC1 | 1:3~1:6 | Negative | Online Inquiry |
KO17424 | GCC1 Knockout cell line (A549) | Human | GCC1 | 1:3~1:4 | Negative | Online Inquiry |
GCC1 Gene Knockout Cell Lines are precisely engineered cellular models that enable researchers to study the biological consequences of GCC1 gene disruption. These cell lines are developed using advanced genome editing technologies, such as CRISPR-Cas9, resulting in the targeted deletion or inactivation of the GCC1 gene. This allows for the investigation of the gene's role in cellular processes, signaling pathways, and its contribution to various diseases, especially within the context of cancer biology and developmental studies.
The main function of GCC1 gene knockout cell lines is to provide a controlled environment where the absence of GCC1 can be observed, facilitating the examination of phenotypic changes, gene expression alterations, and metabolic profiles that arise from the gene's inactivation. Researchers can employ these cell lines to perform loss-of-function studies, unraveling critical insights into GCC1's role in cellular communication and protein trafficking, thereby uncovering potential therapeutic targets.
The scientific importance of GCC1 gene knockout cell lines extends to diverse applications in research and clinical settings. These models are instrumental in drug discovery, pathway analysis, and mechanism-of-action studies. Furthermore, such knockout systems are invaluable for elucidating gene function in disease contexts, enhancing our understanding of complex biological systems.
Compared to traditional knockdown approaches, such as RNA interference, GCC1 gene knockout lines offer more stable, permanent alterations in gene expression, which leads to more reliable and reproducible experimental outcomes. Additionally, the precision of CRISPR-Cas9 technology minimizes off-target effects, ensuring a higher fidelity of gene manipulation.
For researchers and clinicians focused on genetic pathways and their implications in health and disease, GCC1 gene knockout cell lines represent a significant advancement in experimental tools. Their ability to produce robust and relevant data paves the way for innovations in therapeutic strategies.
At our company, we pride ourselves on providing high-quality biological products, driven by our commitment to advancing scientific research. Our expertise in gene editing and cell line development ensures that GCC1 gene knockout cell lines are delivered with the highest standards of reliability and performance, empowering researchers to achieve their goals.
Please note that all services are for research use only. Not intended for any clinical use.
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