Gene: GATB
Official Full Name: glutamyl-tRNA amidotransferase subunit Bprovided by HGNC
Gene Summary: Contributes to glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA(Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 41. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36137 | GATB Knockout cell line (HeLa) | Human | GATB | 1:3~1:6 | Negative | Online Inquiry |
KO36138 | GATB Knockout cell line (HCT 116) | Human | GATB | 1:2~1:4 | Negative | Online Inquiry |
KO36139 | GATB Knockout cell line (HEK293) | Human | GATB | 1:3~1:6 | Negative | Online Inquiry |
KO36140 | GATB Knockout cell line (A549) | Human | GATB | 1:3~1:4 | Negative | Online Inquiry |
GATB Gene Knockout Cell Lines are engineered cellular models designed for the specific ablation of the GATB gene, which encodes the enzyme that participates in critical metabolic pathways associated with cell growth and differentiation. These cell lines are developed using advanced CRISPR/Cas9 gene-editing technologies, ensuring precise and efficient gene knockout, allowing researchers to investigate the functional role of the GATB gene in various biological contexts.
The key functions of GATB Gene Knockout Cell Lines include their utility in dissecting metabolic and signaling pathways that regulate cellular processes. By removing the GATB gene, researchers can evaluate the consequences of its absence on cellular phenotypes, proliferation, and responsiveness to external stimuli. This model is particularly valuable in studies related to metabolic disorders, cancer research, and drug development, where understanding gene function is paramount.
The scientific importance of these cell lines extends to various applications in both research and clinical settings. They facilitate the identification of novel therapeutic targets and the exploration of gene-disease relationships. In particular, GATB knockout models can aid in the development of targeted therapies by providing insights into how targeted disruption might alter disease progression or treatment response.
Compared to alternative cell line models, GATB Gene Knockout Cell Lines offer increased specificity and reliability, reducing off-target effects commonly associated with older gene disruption methodologies. Furthermore, these engineered lines can be readily incorporated into high-throughput screening processes, which enhances their attractiveness to researchers seeking efficient experimental workflows.
For researchers and clinicians alike, GATB Gene Knockout Cell Lines represent a vital resource that streamlines the study of gene function and disease mechanisms. The ability to conduct rigorous, reproducible experiments with precise genetic modifications makes these cell lines an essential tool in translational research.
Our company specializes in providing cutting-edge biological products, and our expertise in gene editing technologies ensures that our GATB Gene Knockout Cell Lines are of the highest quality and precision, empowering the scientific community to achieve their research objectives effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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