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FRK Knockout Cell Lines

Gene: FRK

Official Full Name: fyn related Src family tyrosine kinaseprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37819 FRK Knockout cell line (HeLa) Human FRK 1:3~1:6 Negative Online Inquiry
KO37820 FRK Knockout cell line (HCT 116) Human FRK 1:2~1:4 Negative Online Inquiry
KO37821 FRK Knockout cell line (A549) Human FRK 1:3~1:4 Negative Online Inquiry

Background

FRK Gene Knockout Cell Lines are genetically engineered cell lines that have been selectively modified to disable the expression of the FRK gene, a member of the Src family of tyrosine kinases known to play significant roles in various cellular processes, including signal transduction, proliferation, and apoptosis. This innovative product serves as a critical tool for researchers aiming to explore the physiological and pathological functions of the FRK gene, particularly in cancer research and other diseases where aberrant signaling pathways are implicated.

These cell lines operate through the complete knockout of FRK gene expression, achieved via CRISPR-Cas9 technology. This mechanism allows for precise editing of the genomic sequence, facilitating the study of the resulting phenotypic changes when the FRK signaling pathway is disrupted. Researchers can evaluate cellular behaviors such as growth, migration, and response to therapeutic agents, providing insights into the gene's role in disease mechanisms.

The scientific importance of FRK Gene Knockout Cell Lines lies in their ability to elucidate the contributions of FRK to various biological processes, potentially leading to the identification of novel therapeutic targets and strategies. Their applications span basic research, drug discovery, and translational studies, making them invaluable in both academic and clinical settings.

Compared to conventional methods, such as RNA interference or traditional knockout techniques, FRK Gene Knockout Cell Lines offer enhanced specificity and efficiency, ensuring accurate results without off-target effects. This specificity increases the reliability of experimental findings and accelerates research timelines.

For researchers and clinicians focused on understanding the underlying mechanisms of diseases linked to the FRK gene, utilizing these knockout cell lines provides a powerful approach to investigate therapeutic interventions and potential biomarkers.

Our company prides itself on delivering high-quality, custom-engineered biological products that cater to the specific needs of the scientific community. With extensive expertise in cell line development and gene editing technologies, we are committed to supporting researchers in their quest for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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