Gene: FOXP2
Official Full Name: forkhead box P2provided by HGNC
Gene Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22105 | FOXP2 Knockout cell line (HeLa) | Human | FOXP2 | 1:3~1:6 | Negative | Online Inquiry |
KO22106 | FOXP2 Knockout cell line (HEK293) | Human | FOXP2 | 1:3~1:6 | Negative | Online Inquiry |
FOXP2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the FOXP2 gene, which is closely associated with language and speech development. These knockout lines have undergone precise gene editing to inactivate the FOXP2 gene, allowing researchers to investigate the downstream effects of its absence at a cellular and molecular level. The mechanisms by which FOXP2 influences neural circuits and speech-related behaviors can be explored in detail through these models, providing invaluable insights into the genetic underpinnings of language disorders.
In research and clinical settings, FOXP2 Gene Knockout Cell Lines serve as powerful tools for examining the neurobiological impacts of FOXP2 deficiency. The absence of this gene has been linked to developmental disorders, making these cell lines essential for elucidating the pathways involved in speech and language acquisition. Scientists can utilize these models for drug discovery, genetic studies, and therapeutic interventions aimed at rectifying language impairments, contributing to a broader understanding of neurodevelopmental disorders.
What sets our FOXP2 Gene Knockout Cell Lines apart from alternatives is their high fidelity and reproducibility, achieved through advanced CRISPR-Cas9 genomic editing techniques. These cell lines are well-characterized, ensuring consistency in experimental results, which is critical for validating research findings. Furthermore, our expert team provides comprehensive support and modifications tailored to specific research needs, enabling end-users to maximize the potential of these models.
The value of FOXP2 Gene Knockout Cell Lines lies in their unique ability to bridge fundamental biological research and clinical application in language-related disorders. Their use can lead to significant advancements in targeted therapies and interventions for affected individuals. Backed by [Your Company’s Name] extensive experience in cell line development and a commitment to advancing genetic research, we are dedicated to providing high-quality biological products that empower researchers and clinicians alike in their pursuit of scientific excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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