Gene: FOXO6
Official Full Name: forkhead box O6provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of dendritic spine development and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08214 | FOXO6 Knockout cell line (HeLa) | Human | FOXO6 | 1:3~1:6 | Negative | Online Inquiry |
KO08215 | FOXO6 Knockout cell line (HCT 116) | Human | FOXO6 | 1:2~1:4 | Negative | Online Inquiry |
FOXO6 Gene Knockout Cell Lines are genetically engineered cellular models where the FOXO6 transcription factor gene has been inactivated or eliminated, leading to a significant impact on cellular regulatory pathways. This product serves as a crucial tool for researchers focusing on gene function, cellular growth, and differentiation processes. FOXO6, a member of the Forkhead box O (FOXO) family of transcription factors, plays a vital role in regulating various biological processes, including metabolism, stress resistance, and apoptosis. By utilizing these knockout cell lines, scientists can elucidate the specific functions and signaling pathways associated with FOXO6, providing insights into metabolic diseases, cancer biology, and aging.
The functionality of FOXO6 Gene Knockout Cell Lines is predicated on the absence of the FOXO6 protein, which allows for the observation of phenotypic changes and molecular alterations in response to various biological stimuli. These cell lines enable the dissection of complex regulatory networks, facilitating a deeper understanding of how the loss of FOXO6 influences cellular homeostasis and the potential compensatory mechanisms activated in its absence.
In research and clinical settings, this product holds significant scientific importance as it offers a model for studying the implications of FOXO6 deficiency, particularly in diseases like diabetes and certain malignancies. Its applications stretch across functional genomics, drug discovery, and elucidation of disease mechanisms, thus positioning it as an indispensable resource for researchers seeking groundbreaking insights.
Compared to alternative gene knockout models, FOXO6 Gene Knockout Cell Lines are meticulously validated and characterized, ensuring high specificity and reproducibility of results. This commitment to quality means that researchers can trust the data derived from experiments performed with these cell lines, increasing the reliability of their findings.
The value of FOXO6 Gene Knockout Cell Lines to researchers and clinicians lies in the robust experimental framework they provide for exploring gene function and therapeutic targeting. Enhanced understanding of FOXO6’s role could pave the way for innovative treatments tailored to diseases linked to metabolic flexibility and stress responses.
With a strong foundation in genetic engineering and cell biology, our company is dedicated to providing high-quality biological tools, ensuring that researchers have access to cutting-edge resources like FOXO6 Gene Knockout Cell Lines to advance their projects and contribute to the fields of molecular biology and therapeutics.
Please note that all services are for research use only. Not intended for any clinical use.
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