Gene: FOXC2
Official Full Name: forkhead box C2provided by HGNC
Gene Summary: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37859 | FOXC2 Knockout cell line (HeLa) | Human | FOXC2 | 1:3~1:6 | Negative | Online Inquiry |
FOXC2 Gene Knockout Cell Lines represent a specialized tool for researchers investigating the role of the forkhead box protein C2 (FOXC2) in various biological processes, including development, metabolism, and cancer progression. These cell lines have been engineered to specifically disrupt the FOXC2 gene, allowing scientists to dissect the functional relevance of FOXC2 and its downstream signaling pathways in a controlled environment.
The key mechanism of these cell lines involves the targeted deletion or disruption of the FOXC2 gene using CRISPR-Cas9 technology or other gene-editing approaches. By knocking out FOXC2, researchers can observe alterations in cellular behavior, such as changes in proliferation, differentiation, and migration. This provides invaluable insight into the gene's role in physiological and pathological states, facilitating a deeper understanding of disease mechanisms.
The scientific significance of FOXC2 Gene Knockout Cell Lines is particularly evident in cancer research, where FOXC2 is implicated in epithelial-mesenchymal transition (EMT), a process critical for metastasis. Additionally, these cell lines are useful in metabolic studies, especially concerning adipogenesis and energy homeostasis. Their application extends into pharmaceutical research, where the assessment of drug responses in FOXC2-deficient models can lead to the development of targeted therapies.
What sets these cell lines apart from alternatives on the market is their reliability and specificity in gene knockout, along with extensive characterization data that support reproducibility in experiments. Researchers can trust that these cell lines will yield informative and actionable data due to their high-quality production processes and validation.
FOXC2 Gene Knockout Cell Lines are invaluable assets in the repertoire of researchers and clinicians alike, providing a robust platform for innovative experiments and studies that can translate into clinical advancements. Our expertise in producing high-fidelity biological products ensures that you are equipped with the best tools to drive your research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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