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FNBP1L Knockout Cell Lines

Gene: FNBP1L

Official Full Name: formin binding protein 1 likeprovided by HGNC

Gene Summary: The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17568 FNBP1L Knockout cell line (HeLa) Human FNBP1L 1:3~1:6 Negative Online Inquiry
KO17569 FNBP1L Knockout cell line (HCT 116) Human FNBP1L 1:2~1:4 Negative Online Inquiry
KO17570 FNBP1L Knockout cell line (HEK293) Human FNBP1L 1:3~1:6 Negative Online Inquiry
KO17571 FNBP1L Knockout cell line (A549) Human FNBP1L 1:3~1:4 Negative Online Inquiry

Background

FNBP1L Gene Knockout Cell Lines are highly specialized cellular models engineered to disrupt the functionality of the FNBP1L gene, which plays a pivotal role in cytoskeletal organization and cellular signaling pathways. This product utilizes CRISPR-Cas9 technology to create precise gene knockouts, allowing researchers to investigate the biological implications of FNBP1L loss-of-function. The manipulation of this gene is crucial for understanding its contributions to various cellular processes, including cell adhesion, migration, and differentiation.

The key mechanism behind the FNBP1L Gene Knockout Cell Lines involves the targeted disruption of the FNBP1L coding sequence, resulting in a non-functional protein. This is particularly invaluable for studies focused on cancer biology, neurobiology, and developmental biology, where FNBP1L has been implicated in tumor progression and cellular response to external stimuli. Researchers can explore how the absence of FNBP1L affects cellular behavior and aids in understanding disease mechanisms or therapeutic responses.

The scientific importance of these cell lines lies in their ability to facilitate high-throughput screening of drug candidates and to serve as reliable models for elucidating gene function in a controlled environment. Compared to traditional transfection methods, the CRISPR knockout provides a more efficient and permanent alteration of the genome, greatly enhancing reproducibility and experimental reliability.

For researchers and clinicians, the unique selling points of FNBP1L Gene Knockout Cell Lines include their customized design for specific experimental needs, the potential for detailed functional assays, and their contribution to advancing personalized medicine through the understanding of genetic influences on disease. The use of these cell lines allows for more accurate modeling of human disease states, ultimately driving innovation in therapeutic development.

Our company specializes in providing cutting-edge biological tools that empower the scientific community, and our FNBP1L Gene Knockout Cell Lines exemplify our commitment to quality and precision in research. By offering these advanced cellular models, we support researchers in their quest to unlock the complexities of cellular behavior and contribute to groundbreaking discoveries in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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