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FLII Knockout Cell Lines

Gene: FLII

Official Full Name: FLII actin remodeling proteinprovided by HGNC

Gene Summary: This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37851 FLII Knockout cell line (HeLa) Human FLII 1:3~1:6 Negative Online Inquiry
KO37852 FLII Knockout cell line (HCT 116) Human FLII 1:2~1:4 Negative Online Inquiry
KO37853 FLII Knockout cell line (HEK293) Human FLII 1:3~1:6 Negative Online Inquiry
KO37854 FLII Knockout cell line (A549) Human FLII 1:3~1:4 Negative Online Inquiry

Background

FLII Gene Knockout Cell Lines represent a pivotal resource in the field of molecular biology, specifically designed to facilitate the study of gene function and regulatory mechanisms. These cell lines are engineered to lack the FLII gene, a crucial component in various biological pathways, thereby allowing researchers to observe the phenotypic and functional consequences of its absence. The knockout approach utilizes advanced CRISPR-Cas9 technology to precisely inactivate the target gene, ensuring a high level of specificity and efficiency.

The primary mechanism of action involves the disruption of the FLII gene, which is known to play a significant role in cellular processes such as signal transduction, cytoskeletal dynamics, and cellular proliferation. By studying these knockout cell lines, researchers can investigate how the absence of FLII affects the cellular landscape, including alterations in gene expression profiles, protein interactions, and metabolic functions. This makes the FLII Gene Knockout Cell Lines invaluable for understanding diseases where FLII is implicated, including various cancer types and developmental disorders.

In terms of scientific importance, these cell lines serve as a powerful tool for both fundamental research and potential therapeutic development, enabling scientists to uncover novel insights into gene function and its implications in health and disease. They are particularly advantageous in comparative studies against wild-type cell lines, as they provide clear, controlled environments to evaluate the specific impacts of gene loss.

Distinct from alternative products, FLII Gene Knockout Cell Lines offer unmatched precision, reproducibility, and a user-friendly platform that integrates seamlessly into existing research workflows. The absence of FLII allows for a clear dissection of biological pathways without the confounding influences of wild-type gene expression.

For researchers and clinicians, investing in FLII Gene Knockout Cell Lines means gaining access to a sophisticated toolset that enhances experimental rigor and accelerates the pace of discovery in genetic and biomedical research. With a focus on quality and cutting-edge technology, our company stands at the forefront of providing reliable biological products that empower researchers to make significant contributions to science and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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