Gene: FKBP7
Official Full Name: FKBP prolyl isomerase 7provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22305 | FKBP7 Knockout cell line (HeLa) | Human | FKBP7 | 1:3~1:6 | Negative | Online Inquiry |
KO22306 | FKBP7 Knockout cell line (HCT 116) | Human | FKBP7 | 1:2~1:4 | Negative | Online Inquiry |
KO22307 | FKBP7 Knockout cell line (HEK293) | Human | FKBP7 | 1:3~1:6 | Negative | Online Inquiry |
KO22308 | FKBP7 Knockout cell line (A549) | Human | FKBP7 | 1:3~1:4 | Negative | Online Inquiry |
FKBP7 Gene Knockout Cell Lines are genetically engineered cell lines designed to lack the FKBP7 gene, which encodes a member of the immunophilin family of proteins known for their role in protein folding, trafficking, and mitochondrial function. This knockout effectively eliminates the expression of FKBP7, allowing researchers to study the impact of its absence on cellular processes, signaling pathways, and overall cellular physiology.
The primary function of FKBP7 involves regulating protein stability and modulating responses to stress, particularly within the context of cellular stability against misfolded proteins and stress-induced apoptosis. By utilizing FKBP7 knockout models, scientists can elucidate the gene's specific contributions to various biological processes, including the unfolded protein response, cellular proliferation, differentiation, and apoptosis. The unique mechanisms of FKBP7, particularly its interactions with other proteins involved in crucial pathways, can thus be investigated in a controlled environment.
The scientific importance of FKBP7 Gene Knockout Cell Lines is particularly pronounced in cancer research, neurodegenerative diseases, and metabolic studies, where understanding the role of protein misfolding is critical. By employing these cell lines, researchers are positioned to advance knowledge in therapeutic development, targeting disease mechanisms at a molecular level, and contributing to the understanding of gene function via loss-of-function studies.
When compared to conventional cell lines or other knockout models, FKBP7 knockout cell lines offer a unique value proposition. They provide a precise model for studying FKBP7-related functions without the confounding influences seen in wild-type cells or models with incomplete knockdowns. This enhances reproducibility and reliability, crucial for generating meaningful data in both basic and applied research.
Moreover, these cell lines are invaluable resources for clinicians and researchers working on translational medicine, as they contribute directly to the identification of biomarkers and potential therapeutic targets. Their capacity to accelerate discovery and innovation makes them an essential asset in laboratories worldwide.
As a company dedicated to advancing biological understanding, we pride ourselves on offering high-quality genetic models like the FKBP7 Gene Knockout Cell Lines. Our expertise in cell line development ensures that researchers have the tools they need to explore the complexities of gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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