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FKBP11 Knockout Cell Lines

Gene: FKBP11

Official Full Name: FKBP prolyl isomerase 11provided by HGNC

Gene Summary: FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22708 FKBP11 Knockout cell line (HeLa) Human FKBP11 1:3~1:6 Negative Online Inquiry
KO22709 FKBP11 Knockout cell line (HCT 116) Human FKBP11 1:2~1:4 Negative Online Inquiry
KO22710 FKBP11 Knockout cell line (HEK293) Human FKBP11 1:3~1:6 Negative Online Inquiry
KO22711 FKBP11 Knockout cell line (A549) Human FKBP11 1:3~1:4 Negative Online Inquiry

Background

FKBP11 Gene Knockout Cell Lines are specialized cellular models in which the FKBP11 gene has been specifically disabled or "knocked out" to elucidate its role in cellular processes. This product offers significant insights into the function of FKBP11, which encodes a member of the immunophilin family known to be involved in protein folding and trafficking, as well as cellular stress responses. By utilizing CRISPR-Cas9 technology, our SKBP11 Gene Knockout Cell Lines not only ensure high efficiency in gene disruption but also provide a well-characterized platform for studying the gene's functional associations with various physiological and pathological states.

These knockout cell lines facilitate detailed investigation of FKBP11's role in protein regulation, signal transduction, and stress response mechanisms, making them essential for both basic research and applied sciences. They serve as a vital tool in drug discovery and therapeutic development, particularly in the realms of oncology and neurobiology, where understanding FKBP11's contributions could lead to novel intervention strategies.

Our FKBP11 Gene Knockout Cell Lines feature several advantages when compared to alternative models, including a highly reproducible knockout efficiency, minimal off-target effects, and significant expression stability. Researchers can depend on these lines to generate consistent results across experiments, reducing variability and expediting their findings.

The value of our FKBP11 Gene Knockout Cell Lines extends beyond mere research utility; they can empower researchers and clinicians to unlock new avenues of inquiry, enhance translational research, and ultimately contribute to the development of targeted therapies. With years of expertise in the production and application of biological products, our company is committed to providing high-quality, reliable tools that enhance scientific exploration and promote advances in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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