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FGD3 Knockout Cell Lines

Gene: FGD3

Official Full Name: FYVE, RhoGEF and PH domain containing 3provided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23931 FGD3 Knockout cell line (HCT 116) Human FGD3 1:2~1:4 Negative Online Inquiry

Background

FGD3 Gene Knockout Cell Lines are specialized cellular models created through the targeted disruption of the FGD3 gene, which encodes a protein implicated in various cellular processes including actin cytoskeleton organization and cellular signaling pathways. These knockout cell lines serve as invaluable tools for understanding the functional role of FGD3 in cellular biology and disease mechanisms.

The primary function of FGD3 gene knockout cell lines is to facilitate research into the consequences of FGD3 loss on cell morphology, migration, and proliferation. The mechanism of action relies on CRISPR/Cas9 technology or other gene-editing approaches to ensure precise excision of the FGD3 gene, allowing researchers to study the resultant phenotypic and molecular changes. These insights are crucial for understanding the gene’s involvement in pathological conditions, including developmental disorders and certain cancers.

The scientific importance of these cell lines is underscored by their wide applicability in both basic research and clinical settings. Researchers can utilize FGD3 knockout lines to delineate pathways related to cell motility and invasion, which can inform therapeutic strategies for diseases characterized by aberrant cell movement. Clinically, these lines can assist in the validation of drug targets and the mechanistic investigation of potential treatment strategies.

Compared to existing alternatives, FGD3 Gene Knockout Cell Lines offer a well-defined genetic background that enhances experimental consistency. This specificity allows for more reliable comparisons between experimental groups, thereby increasing the validity of research findings. Additionally, the availability of these knockout lines may significantly accelerate the development of novel therapies targeting the pathways influenced by FGD3.

In summary, FGD3 Gene Knockout Cell Lines are an essential resource for researchers and clinicians aiming to explore the molecular underpinnings of critical cellular functions and disease mechanisms. Our company, with extensive expertise in genetic engineering and cellular model development, is committed to providing high-quality biological research tools, ensuring that you have the best resources to advance your research efforts and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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