Home / FDFT1 Knockout Cell Lines

FDFT1 Knockout Cell Lines

Gene: FDFT1

Official Full Name: farnesyl-diphosphate farnesyltransferase 1provided by HGNC

Gene Summary: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09580 FDFT1 Knockout cell line (HeLa) Human FDFT1 1:3~1:6 Negative Online Inquiry
KO09581 FDFT1 Knockout cell line (HCT 116) Human FDFT1 1:2~1:4 Negative Online Inquiry
KO09582 FDFT1 Knockout cell line (HEK293) Human FDFT1 1:3~1:6 Negative Online Inquiry
KO09583 FDFT1 Knockout cell line (A549) Human FDFT1 1:3~1:4 Negative Online Inquiry

Background

FDFT1 Gene Knockout Cell Lines are genetically modified cell lines that have undergone a targeted disruption of the FDFT1 gene, which encodes for farnesyl diphosphate farnesyltransferase 1, an enzyme critical in the biosynthesis of sterols and isoprenoids. By ablating this gene, researchers can elucidate its roles in cellular mechanisms and lipid metabolism, thereby providing a powerful tool for investigating the pathophysiology of various diseases, including cancer and metabolic disorders.

The primary function of FDFT1 Gene Knockout Cell Lines lies in their ability to facilitate detailed studies on the effects of disrupted sterol biosynthesis pathways. These cell lines exhibit altered cellular responses to lipid signaling, which helps researchers understand the implications of FDFT1 activity in cell proliferation, apoptosis, and differentiation. The knockout of this gene can lead to unmistakable phenotypic changes that serve as a vital point of investigation into how lipids influence cellular behavior in both normal and pathological contexts.

In research and clinical applications, these cell lines stand as a critical resource for drug development and testing, particularly in chemotherapy and targeted therapies that aim to disrupt metabolic cancer pathways. Their utility in functional genomics and pathway validation provides insights that are invaluable for academic studies and translational medicine alike.

What sets our FDFT1 Gene Knockout Cell Lines apart from existing alternatives is their high specificity and robustness, offering a reliable model to study the FDFT1-related signaling cascades without the confounding variables associated with non-targeted models. Furthermore, these lines come with a full suite of accompanying data and protocols, enabling smoother integration into existing research frameworks, thus saving time and resources.

As a leader in the field of genetic engineering and cellular models, our company is dedicated to providing high-quality biological products backed by extensive research and development. Our expertise ensures that researchers and clinicians can confidently rely on our FDFT1 Gene Knockout Cell Lines to advance their work in understanding and treating complex diseases.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.