Gene: FBXO41
Official Full Name: F-box protein 41provided by HGNC
Gene Summary: This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22031 | FBXO41 Knockout cell line (HeLa) | Human | FBXO41 | 1:3~1:6 | Negative | Online Inquiry |
KO22032 | FBXO41 Knockout cell line (HCT 116) | Human | FBXO41 | 1:2~1:4 | Negative | Online Inquiry |
KO22033 | FBXO41 Knockout cell line (A549) | Human | FBXO41 | 1:3~1:4 | Negative | Online Inquiry |
FBXO41 Gene Knockout Cell Lines represent a groundbreaking advancement in gene editing technology, specifically designed to elucidate the function of the FBXO41 gene in cellular processes. These cell lines have been genetically modified to abrogate the expression of the FBXO41 gene, allowing researchers to investigate the phenotypic consequences of its loss. By providing a platform to study FBXO41’s role in cellular functions, these knockout models facilitate the understanding of various biological mechanisms, including mechanisms related to cell cycle regulation, protein ubiquitination, and potential associations with diseases such as cancer.
The mechanism by which FBXO41 Gene Knockout Cell Lines operate hinges on CRISPR/Cas9 gene-editing technology, which introduces targeted double-strand breaks in the genomic DNA, resulting in the disruption of the gene of interest. Researchers can then analyze gene expression profiles, metabolic changes, and downstream signaling pathways in a controlled environment, yielding insights that are critical for experimental reproducibility and accuracy.
In terms of scientific importance, these knockout cell lines are invaluable tools for basic research and preclinical investigations, allowing for a deeper understanding of the physiological roles and molecular pathways associated with FBXO41. They serve as critical assets in functional genomics, providing insight into gene function and its implications in health and disease.
Compared to existing alternatives, FBXO41 Gene Knockout Cell Lines offer high specificity and efficiency in gene disruption. They alleviate potential off-target effects characteristic of earlier gene editing technologies, ensuring precise outcomes that enhance the fidelity of research findings. Moreover, using these cell lines accelerates the pathway from discovery to application, providing a versatile platform for drug screening, biomarker discovery, and mechanistic studies.
For researchers and clinicians focused on understanding gene function or exploring therapeutic avenues, FBXO41 Gene Knockout Cell Lines are indispensable. They not only simplify the process of dissecting complex genetic contributions to disease but also provide reproducible models that enhance the reliability of experimental data.
Our company is at the forefront of innovative biological products, with a commitment to delivering state-of-the-art research tools that empower scientists to unlock new discoveries. Our extensive expertise in gene editing technologies guarantees the highest quality and performance in every cell line we offer, supporting your research endeavors with rigor and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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