Gene: FBXO24
Official Full Name: F-box protein 24provided by HGNC
Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28174 | FBXO24 Knockout cell line (HEK293) | Human | FBXO24 | 1:3~1:6 | Negative | Online Inquiry |
FBXO24 Gene Knockout Cell Lines are genetically engineered cell lines that specifically lack functional expression of the FBXO24 gene, which encodes a member of the F-box protein family involved in protein ubiquitination pathways. This gene plays a critical role in various cellular processes, including cell cycle regulation, apoptosis, and signal transduction, making these knockout cell lines invaluable tools for researchers studying the intricate dynamics of ubiquitin-mediated proteolysis.
The primary function of FBXO24 Gene Knockout Cell Lines is to facilitate investigations into the biological ramifications of the absence of FBXO24. Researchers utilize these cells to dissect the pathways influenced by this gene, enabling the elucidation of its role in cellular mechanisms such as differentiation, tumorigenesis, and stress responses. knockouts can yield insights into disease pathways associated with aberrant FBXO24 activity, potentially identifying therapeutic targets for a variety of malignancies and other disorders.
In research and clinical settings, FBXO24 knockout models offer significant advantages over conventional models, such as wild-type cell lines, by providing clearer and more specific insights into gene function and its biological consequences. Their unique ability to mimic loss-of-function mutations allows for the assessment of FBXO24's contributions to pathophysiology and drug responses with higher fidelity. This precision makes them preferable for high-throughput screening and the development of novel therapeutic strategies.
Researchers and clinicians can derive exceptional value from utilizing FBXO24 Gene Knockout Cell Lines due to their rigorously validated performance and the depth of understanding they bring to molecular biology and pharmacology investigations. These cell lines are particularly beneficial for those examining cancer biology and cellular signaling networks, as they can accelerate discovery efforts and facilitate the validation of hypotheses in a controlled environment.
Our company has extensive expertise in genetic engineering and the development of innovative biological products, ensuring that our FBXO24 Gene Knockout Cell Lines meet the highest standards of quality and reliability for your research needs. We are committed to supporting the scientific community with advanced tools that drive breakthroughs in understanding gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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