Home / FAF1 Knockout Cell Lines

FAF1 Knockout Cell Lines

Gene: FAF1

Official Full Name: Fas associated factor 1provided by HGNC

Gene Summary: Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31185 FAF1 Knockout cell line (HeLa) Human FAF1 1:3~1:6 Negative Online Inquiry
KO31186 FAF1 Knockout cell line (HCT 116) Human FAF1 1:2~1:4 Negative Online Inquiry
KO31187 FAF1 Knockout cell line (HEK293) Human FAF1 1:3~1:6 Negative Online Inquiry
KO31188 FAF1 Knockout cell line (A549) Human FAF1 1:3~1:4 Negative Online Inquiry

Background

FAF1 Gene Knockout Cell Lines are genetically engineered cell lines that have had the FAF1 (Fas-Associated Factor 1) gene inactivated through targeted gene editing techniques. FAF1 is a critical regulator of apoptosis, playing a significant role in cellular response to stress and inflammation. By knocking out this gene, researchers can investigate the implications of FAF1 deficiency on various biological pathways, providing insights into disease mechanisms related to cancer, neurodegenerative disorders, and immune responses.

These cell lines function as invaluable tools for studying cellular processes such as apoptosis, signaling pathways, and tumorigenesis. The absence of FAF1 allows for the delineation of its role in modulating the balance between cell survival and programmed cell death, thus revealing potential therapeutic targets for intervention. Researchers can utilize these knockout cell lines to conduct functional assays, drug screening, and validation of gene therapies, facilitating a deeper understanding of cellular homeostasis and pathophysiology.

The scientific importance of FAF1 Gene Knockout Cell Lines extends to both basic and translational research. In clinical settings, they are instrumental for developing novel therapeutic strategies aimed at manipulating apoptosis in malignancies where FAF1 signaling may be disrupted. Compared to other knockout models, these cell lines offer a high level of specificity and reproducibility, aided by modern genome-editing technologies, thus enhancing the reliability of experimental results.

Researchers and clinicians stand to gain significantly by incorporating FAF1 Knockout Cell Lines into their studies. Their unique capacity to simulate disease states by mimicking genetic mutations found in patients positions them as a strategic asset for advancing personalized medicine. Furthermore, in contrast to traditional cell lines, these knockout models provide a clearer interpretation of gene function, ultimately propelling innovation in therapeutic approaches.

Our company specializes in the development of cutting-edge biological products tailored to meet the diverse needs of the research community. With a commitment to quality and scientific rigor, we provide researchers and clinicians with the tools necessary to explore complex biological questions, paving the way for breakthrough discoveries and advancements in healthcare.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.