Gene: FAAP20
Official Full Name: FA core complex associated protein 20provided by HGNC
Gene Summary: Enables K63-linked polyubiquitin modification-dependent protein binding activity and ubiquitin-modified protein reader activity. Involved in interstrand cross-link repair and translesion synthesis. Located in cell junction; chromosome; and nuclear body. Part of Fanconi anaemia nuclear complex and chromatin. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21272 | FAAP20 Knockout cell line (HeLa) | Human | FAAP20 | 1:3~1:6 | Negative | Online Inquiry |
KO21273 | FAAP20 Knockout cell line (HCT 116) | Human | FAAP20 | 1:2~1:4 | Negative | Online Inquiry |
KO21274 | FAAP20 Knockout cell line (HEK293) | Human | FAAP20 | 1:3~1:6 | Negative | Online Inquiry |
KO21275 | FAAP20 Knockout cell line (A549) | Human | FAAP20 | 1:3~1:4 | Negative | Online Inquiry |
FAAP20 Gene Knockout Cell Lines represent a breakthrough in the field of cellular and molecular biology, specifically engineered to elucidate the role of the FAAP20 gene in DNA repair and cellular response to stress. These knockout cell lines are derived from established cell lines, where the FAAP20 gene has been precisely disrupted through CRISPR-Cas9 technology, ensuring that researchers can effectively study the absence of this gene's function in various biological contexts.
The key mechanism underlying the FAAP20 Gene Knockout Cell Lines is their ability to elucidate the gene's involvement in the Fanconi Anemia pathway, which is crucial for DNA repair mechanisms and the maintenance of genomic stability. By utilizing these knockout models, researchers can observe alterations in cellular behaviors such as proliferation, apoptosis, and response to genotoxic stresses. This can help decipher the molecular underpinnings of Fanconi Anemia-related disorders, providing insights vital for developing new therapeutic avenues.
The scientific significance of FAAP20 Gene Knockout Cell Lines is evident in both research and clinical settings, as they enable the exploration of gene-function relationships and pathological mechanisms associated with cancer and genetic diseases. Additionally, their use extends to drug testing and biomarker discovery, which are pivotal in translational medicine.
Compared to alternative models, FAAP20 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, ensuring that experimental outcomes are directly attributable to the disruption of the FAAP20 gene itself. This level of precision is often lacking in conventional pharmacological or gene overexpression methods, making these cell lines an invaluable resource for scientists aiming to uncover the nuances of gene action within biological systems.
For researchers and clinicians seeking to advance their understanding of DNA repair mechanisms and associated disorders, the FAAP20 Gene Knockout Cell Lines provide a robust and reliable platform. Their implementation promises to streamline experimental procedures while enhancing data accuracy. Our company prides itself on its commitment to scientific excellence and innovation, providing high-quality biological products that empower research and drive meaningful discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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