Gene: ERMAP
Official Full Name: erythroblast membrane associated protein (Scianna blood group)provided by HGNC
Gene Summary: The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30785 | ERMAP Knockout cell line (HeLa) | Human | ERMAP | 1:3~1:6 | Negative | Online Inquiry |
KO30786 | ERMAP Knockout cell line (HCT 116) | Human | ERMAP | 1:2~1:4 | Negative | Online Inquiry |
KO30787 | ERMAP Knockout cell line (HEK293) | Human | ERMAP | 1:3~1:6 | Negative | Online Inquiry |
KO30788 | ERMAP Knockout cell line (A549) | Human | ERMAP | 1:3~1:4 | Negative | Online Inquiry |
ERMAP Gene Knockout Cell Lines are specifically designed cellular models that enable researchers to investigate the role of the ERMAP gene, a critical regulator of cell adhesion and immune response. By employing CRISPR-Cas9 gene-editing technology, these knockout cell lines have been meticulously engineered to remove the ERMAP gene, facilitating the study of its physiological and pathological functions in various biological contexts.
The primary function of the ERMAP Gene Knockout Cell Lines lies in their ability to replicate the effects of ERMAP deficiency, allowing for comprehensive analysis in areas such as cancer biology, immunology, and stem cell research. These models serve as invaluable tools for elucidating cellular signaling pathways and exploring the implications of ERMAP in cell migration, immune evasion, and tumor development. The mechanistic insights gained from using these cell lines can lead to groundbreaking discoveries in targeted therapies and personalized medicine.
In terms of scientific importance, ERMAP Gene Knockout Cell Lines are instrumental in both research and clinical settings. They enable the identification of potential biomarkers and therapeutic targets, which can significantly enhance the understanding of diseases associated with altered cell adhesion mechanisms. Furthermore, their use can streamline drug development processes by providing pertinent preclinical data regarding the efficacy of novel compounds.
What sets these knockout cell lines apart from existing products on the market is their high reliability and consistency, coupled with the ease of integration into various experimental workflows. Researchers can benefit from an efficient tool that reduces time and resource expenditure while delivering robust and reproducible results. Moreover, the specificity of the gene knockout aids in minimizing off-target effects that could confound experimental outcomes.
For researchers and clinicians alike, the ERMAP Gene Knockout Cell Lines represent a powerful asset in the quest to decipher complex biological processes and advance therapeutic strategies. By providing these sophisticated tools, our company demonstrates a commitment to enhancing scientific inquiry and fostering innovations in health and medicine, anchored by years of expertise in developing high-quality biological products that meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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