Gene: EPS8L2
Official Full Name: EPS8 signaling adaptor L2provided by HGNC
Gene Summary: This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17931 | EPS8L2 Knockout cell line (HeLa) | Human | EPS8L2 | 1:3~1:6 | Negative | Online Inquiry |
KO17932 | EPS8L2 Knockout cell line (HCT 116) | Human | EPS8L2 | 1:2~1:4 | Negative | Online Inquiry |
KO17933 | EPS8L2 Knockout cell line (HEK293) | Human | EPS8L2 | 1:3~1:6 | Negative | Online Inquiry |
KO17934 | EPS8L2 Knockout cell line (A549) | Human | EPS8L2 | 1:3~1:4 | Negative | Online Inquiry |
EPS8L2 Gene Knockout Cell Lines are advanced research tools designed to study the functional implications of the EPS8L2 gene in various biological processes. These cell lines are meticulously engineered to eliminate the expression of the EPS8L2 gene, allowing researchers to observe the resulting phenotypic changes and investigate the underlying molecular mechanisms. By utilizing CRISPR-Cas9 technology, these knockout models provide a reliable and precise method for gene disruption, enabling a deeper understanding of EPS8L2's role in cellular signaling pathways, cell growth, differentiation, and potential involvement in disease states.
The primary mechanism of the EPS8L2 Gene Knockout Cell Lines operates through targeted genomic modification. Upon introduction of the CRISPR-Cas9 components, specific double-strand breaks are created at the EPS8L2 locus, followed by the cellular repair processes that lead to gene disruption. This results in the absence of functional EPS8L2 protein, allowing accurate assessments of its role in physiological and pathological contexts, such as cancer biology, neurobiology, and cellular response to stress.
The scientific importance of EPS8L2 Gene Knockout Cell Lines extends to their applications in both basic research and clinical translational studies. Researchers can utilize these lines to explore the gene's contribution to tumorigenesis or as a potential therapeutic target. Moreover, these knockout models are integral in identifying novel biomarkers for disease progression and treatment responses, thus advancing personalized medicine strategies.
Compared to traditional knockout methods, the EPS8L2 Gene Knockout Cell Lines offer unparalleled precision, reduced off-target effects, and a faster time to experimental completion. This specificity enhances the reliability of experimental data, making them a preferred choice for researchers focused on elucidating gene function and pathway involvement.
Ultimately, the value of EPS8L2 Gene Knockout Cell Lines lies in their capability to significantly advance scientific inquiry within academia and industry. By providing a robust platform for gene function analysis, these cell lines empower researchers and clinicians alike to push the boundaries of knowledge and treatment in diverse biological fields. Our company, renowned for its commitment to high-quality biological products and cutting-edge technologies, is proud to offer these innovative cell lines, thus supporting the scientific community in their pursuit of groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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