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EPHX4 Knockout Cell Lines

Gene: EPHX4

Official Full Name: epoxide hydrolase 4provided by HGNC

Gene Summary: Predicted to enable hydrolase activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21243 EPHX4 Knockout cell line (HCT 116) Human EPHX4 1:2~1:4 Negative Online Inquiry
KO21244 EPHX4 Knockout cell line (HEK293) Human EPHX4 1:3~1:6 Negative Online Inquiry
KO21245 EPHX4 Knockout cell line (A549) Human EPHX4 1:3~1:4 Negative Online Inquiry

Background

EPHX4 Gene Knockout Cell Lines are specifically engineered cellular models that have had the EPHX4 gene inactivated, providing researchers with a valuable tool for studying the physiological and pathological roles of this gene. EPHX4, also known as epoxide hydrolase 4, is involved in the metabolism of various lipid mediators and plays a crucial role in inflammation and vascular health. By employing targeted gene editing techniques, these cell lines permit the exploration of EPHX4’s functions in detail, enabling scientists to assess the downstream effects of its absence on cellular processes such as oxidative stress response, cell proliferation, and apoptotic signaling.

The primary mechanism of EPHX4 knockout involves the disruption of the gene's coding sequence, effectively creating a loss-of-function phenotype in the engineered cell lines. This allows for an improved understanding of EPHX4's contribution to disease states, especially in models relating to cardiovascular disorders and cancer. The availability of these knockout cell lines opens up significant avenues in innovative research, allowing for the exploration of therapeutic targets and the development of potential treatment modalities.

What sets EPHX4 Gene Knockout Cell Lines apart from other available models is their specificity and the precision of the gene-editing techniques used to create them. Unlike traditional knockout models that may introduce variability, these lines provide consistency and reproducibility in experimental outcomes, thereby enhancing the reliability of research findings.

Researchers and clinicians benefit immensely from these cell lines, as they can expedite the investigation into the role of EPHX4 in various biological processes and accelerate drug discovery pipelines. The clarity of data derived from using these models can lead to a deeper understanding of disease mechanisms and foster the development of novel therapeutic approaches.

At [Company Name], we pride ourselves on our commitment to providing high-quality biological products tailored for cutting-edge research. Our expertise in gene editing and cell line development ensures that you have access to robust, reliable models that empower scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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