Gene: EPDR1
Official Full Name: ependymin related 1provided by HGNC
Gene Summary: The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17950 | EPDR1 Knockout cell line (HeLa) | Human | EPDR1 | 1:3~1:6 | Negative | Online Inquiry |
KO17951 | EPDR1 Knockout cell line (HCT 116) | Human | EPDR1 | 1:2~1:4 | Negative | Online Inquiry |
KO17952 | EPDR1 Knockout cell line (HEK293) | Human | EPDR1 | 1:3~1:6 | Negative | Online Inquiry |
KO17953 | EPDR1 Knockout cell line (A549) | Human | EPDR1 | 1:3~1:4 | Negative | Online Inquiry |
EPDR1 Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the functions of the EPDR1 gene, known for its involvement in various biological processes, including cellular differentiation and receptor signaling. By employing CRISPR-Cas9 technology, these cell lines achieve a precise knockout of the EPDR1 gene, allowing researchers to investigate the downstream effects of its absence on cellular behavior and gene expression.
The primary function of the EPDR1 gene knockout is to enable detailed examination of physiological changes that occur when EPDR1 is inactive. This facilitates research into pathways that affect cell proliferation, immune response, and metabolic regulation. Mechanistically, the knockout cells reveal altered signaling cascades and provide insights into compensatory mechanisms that may be activated in the absence of the EPDR1 protein. Such capabilities are invaluable in elucidating the potential therapeutic targets for diseases linked to EPDR1 dysfunction.
In terms of scientific importance, EPDR1 Gene Knockout Cell Lines serve as crucial tools in both fundamental and applied research settings. They can be employed in drug development, disease modeling, and the exploration of gene function in various physiological contexts. Their application extends into studies of cancer, neurodegenerative disorders, and autoimmune diseases, where understanding the role of EPDR1 is essential for therapeutic advancement.
Compared to traditional cell lines, these knockout models offer a significant advantage by providing a platform for high-throughput screening and functional genomic studies, enabling researchers to rapidly assess the effects of experimental treatments and investigate gene interactions. Moreover, the precision of the CRISPR-Cas9 technology ensures reproducibility and specificity of gene editing, setting these cell lines apart from other gene manipulation methods.
For researchers and clinicians dedicated to unraveling the complexities of cellular signaling and gene regulation, EPDR1 Gene Knockout Cell Lines present a unique opportunity to not only deepen scientific understanding but also contribute to the development of innovative therapeutic strategies. Our company is committed to advancing research tools and provides extensive technical support, ensuring that our customers can maximize the potential of our biological products in their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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