Gene: EPB41L4A
Official Full Name: erythrocyte membrane protein band 4.1 like 4Aprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17958 | EPB41L4A Knockout cell line (HeLa) | Human | EPB41L4A | 1:3~1:6 | Negative | Online Inquiry |
KO17959 | EPB41L4A Knockout cell line (HCT 116) | Human | EPB41L4A | 1:2~1:4 | Negative | Online Inquiry |
KO17960 | EPB41L4A Knockout cell line (HEK293) | Human | EPB41L4A | 1:3~1:6 | Negative | Online Inquiry |
KO17961 | EPB41L4A Knockout cell line (A549) | Human | EPB41L4A | 1:3~1:4 | Negative | Online Inquiry |
EPB41L4A Gene Knockout Cell Lines are genetically engineered model systems that have undergone targeted gene disruption to disable the EPB41L4A gene, which is implicated in various cellular functions, including cytoskeletal organization and cellular signaling pathways. By removing the expression of this gene, these cell lines provide researchers with a valuable tool for studying the consequences of EPB41L4A loss on cellular behaviors such as proliferation, migration, and differentiation.
The functionality of EPB41L4A Gene Knockout Cell Lines lies in their ability to mimic disease states where EPB41L4A is downregulated or absent. Researchers utilize these knockout models to elucidate the gene’s role in cellular physiology, identify downstream signaling pathways affected by its absence, and investigate potential compensatory mechanisms that cells may employ. This functionality is particularly critical in understanding diseases such as cancer, where cytoskeletal dynamics play a pivotal role in tumor progression and metastasis.
The scientific importance of these cell lines extends to both basic research and clinical applications. They serve as a platform for drug discovery, toxicology studies, and the development of therapeutic strategies that target the aberrant pathways associated with EPB41L4A dysfunction. By creating conditions that closely resemble pathological states, researchers can gain insights that are more translatable to human health outcomes.
Compared to alternative models, such as wild-type cell lines or transient knockdown approaches, EPB41L4A Gene Knockout Cell Lines offer more stable and reproducible results, allowing for prolonged studies and the assessment of long-term cellular responses. This permanence facilitates deeper investigations into the gene's role under varied experimental conditions, providing superior data integrity.
For researchers, clinicians, and other end-users, the use of EPB41L4A Gene Knockout Cell Lines translates to significant advances in uncovering molecular mechanisms that underlie critical biological processes and diseases. The insights gained from utilizing these cell lines can ultimately lead to innovative therapeutic solutions and improved patient outcomes.
As a company dedicated to advancing genetic research tools, we pride ourselves on our expertise in developing high-quality, reliable biological products like the EPB41L4A Gene Knockout Cell Lines. We strive to empower the scientific community through innovative solutions that enhance research efficiency and accelerate discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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