Gene: ENO2
Official Full Name: enolase 2provided by HGNC
Gene Summary: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08237 | ENO2 Knockout cell line (HeLa) | Human | ENO2 | 1:3~1:6 | Negative | Online Inquiry |
KO08238 | ENO2 Knockout cell line (HCT 116) | Human | ENO2 | 1:2~1:4 | Negative | Online Inquiry |
KO08239 | ENO2 Knockout cell line (HEK293) | Human | ENO2 | 1:3~1:6 | Negative | Online Inquiry |
KO08240 | ENO2 Knockout cell line (A549) | Human | ENO2 | 1:3~1:4 | Negative | Online Inquiry |
ENO2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the enolase 2 (ENO2) gene, which encodes an enzyme involved in glycolysis. These knockout cell lines are invaluable tools for understanding the biological roles that ENO2 plays in various cellular processes, including metabolism, cell proliferation, and survival under stress conditions. By effectively silencing the ENO2 gene, researchers can directly study the functional consequences of its absence, facilitating investigations into cancer biology, neurodegenerative diseases, and metabolic disorders.
The key mechanism behind these cell lines involves precise gene-editing techniques, such as CRISPR-Cas9, which allow for efficient and specific deletion of target genes. This provides researchers with a controlled system to analyze alterations in metabolic pathways and cellular responses, offering deeper insights into how ENO2 contributes to physiological and pathological states. The availability of these models is crucial for elucidating the enzyme's role in tumorigenesis and identifying potential therapeutic targets.
The scientific importance of ENO2 Gene Knockout Cell Lines cannot be overstated as they pave the way for novel research avenues in both in vitro and potentially in vivo settings. They enable researchers to explore new hypotheses related to cancer metabolism, neuroprotection, and the metabolic adaptations of cells under various stressors. Compared to alternative models, these knockout cell lines provide a more definitive approach to gene function analysis, offering a clear delineation of ENO2's contributions without the confounding effects of other variables.
For researchers and clinicians, the value of ENO2 Gene Knockout Cell Lines lies in their capacity to enhance experimental rigor and reproducibility. These cell lines allow for more precise experimentation, leading to better validation of hypotheses and quicker translation of findings into clinical practice.
Our company prides itself on its expertise in developing high-quality biological models designed to meet the needs of the research community. With a commitment to innovation and rigorous quality control, we ensure that our products, including ENO2 Gene Knockout Cell Lines, provide the essential tools that drive scientific discovery forward.
Please note that all services are for research use only. Not intended for any clinical use.
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