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EFHD2 Knockout Cell Lines

Gene: EFHD2

Official Full Name: EF-hand domain family member D2provided by HGNC

Gene Summary: Enables cadherin binding activity. Predicted to be located in membrane raft. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18053 EFHD2 Knockout cell line (HeLa) Human EFHD2 1:3~1:6 Negative Online Inquiry
KO18054 EFHD2 Knockout cell line (HCT 116) Human EFHD2 1:2~1:4 Negative Online Inquiry
KO18055 EFHD2 Knockout cell line (HEK293) Human EFHD2 1:3~1:6 Negative Online Inquiry
KO18056 EFHD2 Knockout cell line (A549) Human EFHD2 1:3~1:4 Negative Online Inquiry

Background

EFHD2 Gene Knockout Cell Lines are genetically engineered human or mouse cell lines specifically designed to lack the EFHD2 gene, an important player in cellular signaling and response mechanisms. These knockout models facilitate the study of the EFHD2 protein's functions, which have been implicated in various physiological processes, including neuronal development and synaptic plasticity. By providing a controlled environment to investigate the absence of this gene, researchers can elucidate the underlying mechanisms of EFHD2-related pathways and their roles in health and disease.

The key function of EFHD2 gene knockout cell lines lies in their ability to provide insights into EFHD2 interactions within the cellular milieu. Upon deletion of the EFHD2 gene, one can observe changes in various signaling pathways, analyze shifts in cytoskeletal dynamics, and assess alterations in gene expression profiles. This is particularly advantageous in studies relating to neurodegenerative diseases, where EFHD2's influence on cellular stress responses has been frequently highlighted.

Scientifically, these knockout cell lines are invaluable for both fundamental research and translational applications. In academic research settings, they pave the way for investigations into cellular mechanisms of neuroprotection and regeneration. Clinically, they hold potential in assessing therapeutic targets for conditions tied to dysfunctional EFHD2 expression, offering a pathway for drug development and personalized medicine approaches.

Compared to traditional gene editing techniques, EFHD2 Gene Knockout Cell Lines provide a stable and reproducible model with less variability, enabling consistent results in experiments. This reliability can significantly reduce experimental noise, enhancing the robustness of findings that depend on specific gene functions.

Researchers and clinicians seeking to unravel the complexities of neurobiology and signaling pathways will find these knockout cell lines to be a powerful tool in their investigative arsenal. They offer a unique opportunity to leverage an accurate model for mechanistic explorations and therapeutic advancements.

At [Your Company Name], we pride ourselves on our expertise in genetic engineering and our commitment to enhancing research capabilities through high-quality biological products. Our EFHD2 Gene Knockout Cell Lines are meticulously validated and are tailored to support your research endeavors, ensuring you can drive innovation in your work.

Please note that all services are for research use only. Not intended for any clinical use.

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